Giving New Hope to Children with Liver Cancer Through Innovative Treatment
NCT04634357 · RecruitingThis trial is looking at a new treatment called ET140203 T cells for children with specific liver cancers, including hepatoblastoma and hepatocellular carcinoma. The main goal is to assess how safe the treatment is and find the best dose to use. Participants will be monitored closely over two years to check how well the treatment works and its effects on their health.
Locations and contact
This trial is running at 2 locations in the United States. All of them are currently recruiting.
United States2 locations · 2 recruiting
- Dana-Farber/Boston Children's Cancer and Blood Disorders CenterBoston, MassachusettsRecruiting
- UCSF Benioff Children's HospitalsSan Francisco, CaliforniaRecruiting
Who can join
Children aged 1 to 21 years with certain types of liver cancer can join. They need to have shown that their cancer is not responding to standard treatments. Not everyone can participate; for example, those who can have their tumors completely removed or have other serious health issues may not be eligible. The trial team will confirm who can join.
What happens during the trial
Everyone in the trial will receive the ET140203 T cells as part of the treatment. This means there is no random assignment to different groups. The treatment will be monitored closely to see how participants respond and if there are any side effects.
The trial team
Eureka Therapeutics Inc. is leading this trial. Dr. Pei Wang is the study director overseeing the research.
Important dates
The trial began on July 19, 2022, and is expected to be completed by January 31, 2028. It is currently recruiting new participants.
Additional information
The trial's ID number is NCT04634357. This is a Phase 1/2 trial, which means it is testing how well the treatment works and checking for safety. The treatment is regulated by the FDA, and the trial aims to include about 15 participants.
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