Helping Patients with Head and Neck Cancer Reduce Mouth Sores During Treatment
NCT06532279 · RecruitingAbout this trial
This clinical trial is looking at how well a new drug called BMX-001 works when added to the usual care for patients with head and neck cancer. The main goal is to see if BMX-001 helps lower the number of mouth sores that can happen during treatment. Mouth sores can be painful and make it hard to eat or swallow, so finding ways to reduce them is very important for patients receiving chemoradiation therapy.
Locations and contact
This trial is running at 153 locations in the United States. 146 of them are currently recruiting.
United States153 locations · 146 recruiting
- Adams Cancer CenterGettysburg, PennsylvaniaRecruiting
- Arizona Center for Cancer CareTempe, ArizonaRecruiting
- Arizona Center for Cancer Care - GilbertGilbert, ArizonaRecruiting
- Arizona Center for Cancer Care - PhoenixPhoenix, ArizonaRecruiting
- Arizona Center for Cancer Care - ScottsdaleScottsdale, ArizonaRecruiting
- Arizona Center for Cancer Care-PeoriaPeoria, ArizonaRecruiting
- Arizona Center for Cancer Care-SurpriseSurprise, ArizonaRecruiting
- Aspirus Cancer Care - James Beck Cancer CenterRhinelander, WisconsinRecruiting
- Aspirus Cancer Care - Stevens PointStevens Point, WisconsinRecruiting
- Aspirus Cancer Care - Wisconsin RapidsWisconsin Rapids, WisconsinRecruiting
- Aspirus Regional Cancer CenterWausau, WisconsinRecruiting
- Atrium Health Cabarrus/LCI-ConcordConcord, North CarolinaRecruiting
- Atrium Health Cleveland/LCI-ClevelandShelby, North CarolinaRecruiting
- Atrium Health Pineville/LCI-PinevilleCharlotte, North CarolinaRecruiting
- Atrium Health Stanly/LCI-AlbemarleAlbemarle, North CarolinaRecruiting
- Atrium Health Union/LCI-UnionMonroe, North CarolinaRecruiting
- Atrium Health University City/LCI-UniversityCharlotte, North CarolinaRecruiting
- Aultman Health FoundationCanton, OhioRecruiting
- Baptist Cancer Center-GrenadaGrenada, MississippiRecruiting
- Baptist Health FloydNew Albany, IndianaRecruiting
- Baptist Health HardinElizabethtown, KentuckyRecruiting
- Baptist Memorial Hospital and Cancer Center-ColliervilleCollierville, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-DesotoSouthhaven, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Golden TriangleColumbus, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-MemphisMemphis, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-OxfordOxford, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, MississippiRecruiting
- Boston Medical CenterBoston, MassachusettsRecruiting
- Carle at The RiverfrontDanville, IllinoisRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
- Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
- Carolinas Medical Center/Levine Cancer InstituteCharlotte, North CarolinaRecruiting
- CaroMont Regional Medical CenterGastonia, North CarolinaRecruiting
- Chambersburg HospitalChambersburg, PennsylvaniaRecruiting
- Dartmouth Cancer Center - NorthSaint Johnsbury, VermontRecruiting
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
- Drexel Town Square Health CenterOak Creek, WisconsinRecruiting
- Duke University Medical CenterDurham, North CarolinaRecruiting
- Ephrata Cancer CenterEphrata, PennsylvaniaRecruiting
- Florida Cancer Specialists - SarasotaSarasota, FloridaRecruiting
- Florida Cancer Specialists - Sarasota DowntownSarasota, FloridaRecruiting
- Florida Cancer Specialists - Venice PinebrookVenice, FloridaRecruiting
- Froedtert Menomonee Falls HospitalMenomonee Falls, WisconsinRecruiting
- Froedtert West Bend Hospital/Kraemer Cancer CenterWest Bend, WisconsinRecruiting
- George Washington University Medical CenterWashington D.C., District of ColumbiaRecruiting
- Greater Baltimore Medical CenterBaltimore, MarylandRecruiting
- Hayworth Cancer CenterHigh Point, North CarolinaRecruiting
- Illinois CancerCare - WashingtonWashington, IllinoisRecruiting
- Illinois CancerCare-BloomingtonBloomington, IllinoisRecruiting
- Illinois CancerCare-CantonCanton, IllinoisRecruiting
- Illinois CancerCare-EurekaEureka, IllinoisRecruiting
- Illinois CancerCare-GalesburgGalesburg, IllinoisRecruiting
- Illinois CancerCare-Kewanee ClinicKewanee, IllinoisRecruiting
- Illinois CancerCare-MacombMacomb, IllinoisRecruiting
- Illinois CancerCare-Ottawa ClinicOttawa, IllinoisRecruiting
- Illinois CancerCare-PekinPekin, IllinoisRecruiting
- Illinois CancerCare-PeoriaPeoria, IllinoisRecruiting
- Illinois CancerCare-PeruPeru, IllinoisRecruiting
- Illinois CancerCare-PrincetonPrinceton, IllinoisRecruiting
- Iowa Methodist Medical CenterDes Moines, IowaRecruiting
- Karmanos Cancer Institute at McLaren Greater LansingLansing, MichiganRecruiting
- Lake Regional HospitalOsage Beach, MissouriRecruiting
- Lancaster Radiation Therapy CenterLancaster, South CarolinaRecruiting
- Langlade Hospital and Cancer CenterAntigo, WisconsinRecruiting
- Levine Cancer Institute-GastonGastonia, North CarolinaRecruiting
- Levine Cancer Institute-Rock HillRock Hill, South CarolinaRecruiting
- McFarland Clinic - AmesAmes, IowaRecruiting
- McLaren Cancer Institute-Bay CityBay City, MichiganRecruiting
- McLaren Cancer Institute-Central MichiganMount Pleasant, MichiganRecruiting
- McLaren Cancer Institute-ClarkstonClarkston, MichiganRecruiting
- McLaren Cancer Institute-FlintFlint, MichiganRecruiting
- McLaren Cancer Institute-Lapeer RegionLapeer, MichiganRecruiting
- McLaren Cancer Institute-MacombMount Clemens, MichiganRecruiting
- McLaren Cancer Institute-Northern MichiganPetoskey, MichiganRecruiting
- McLaren-Port HuronPort Huron, MichiganRecruiting
- Medical College of WisconsinMilwaukee, WisconsinRecruiting
- Mercy HospitalCedar Rapids, IowaRecruiting
- Mercy Medical Center - Des MoinesDes Moines, IowaRecruiting
- Miller-Dwan HospitalDuluth, MinnesotaRecruiting
- Moffitt Cancer CenterTampa, FloridaRecruiting
- Moffitt Cancer Center - McKinley CampusTampa, FloridaRecruiting
- Moffitt Cancer Center at SouthShoreRuskin, FloridaRecruiting
- Moffitt Cancer Center at Wesley ChapelWesley Chapel, FloridaRecruiting
- Moffitt Cancer Center-International PlazaTampa, FloridaRecruiting
- Montefiore Medical Center - Moses CampusThe Bronx, New YorkRecruiting
- Montefiore Medical Center-Einstein CampusThe Bronx, New YorkRecruiting
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, ArkansasRecruiting
- Northwest Wisconsin Cancer CenterAshland, WisconsinRecruiting
- Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
- Northwestern Medicine Oak BrookOak Brook, IllinoisRecruiting
- Northwestern Medicine Orland ParkOrland Park, IllinoisRecruiting
- Northwestern UniversityChicago, IllinoisRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- Oncology Associates at Mercy Medical CenterCedar Rapids, IowaRecruiting
- OSF Saint Francis Medical CenterPeoria, IllinoisRecruiting
- OSF Saint Joseph Medical CenterBloomington, IllinoisRecruiting
- Penn State Milton S Hershey Medical CenterHershey, PennsylvaniaRecruiting
- Renown Regional Medical CenterReno, NevadaRecruiting
- Rock Hill Radiation Therapy CenterRock Hill, South CarolinaRecruiting
- Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
- Salina Regional Health CenterSalina, KansasRecruiting
- Sarasota Memorial Health Care Center at University ParkwaySarasota, FloridaRecruiting
- Sarasota Memorial HospitalSarasota, FloridaRecruiting
- Sarasota Memorial Hospital-VeniceN. Venice, FloridaRecruiting
- Sechler Family Cancer CenterLebanon, PennsylvaniaRecruiting
- Shaw Cancer CenterEdwards, ColoradoRecruiting
- Summa Health System - Akron CampusAkron, OhioRecruiting
- UC San Diego Health System - EncinitasEncinitas, CaliforniaRecruiting
- UC San Diego Medical Center - HillcrestSan Diego, CaliforniaRecruiting
- UC San Diego Moores Cancer CenterLa Jolla, CaliforniaRecruiting
- UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, IowaRecruiting
- UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, IowaRecruiting
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, OhioRecruiting
- University of Cincinnati Cancer Center-West ChesterWest Chester, OhioRecruiting
- University of Iowa/Holden Comprehensive Cancer CenterIowa City, IowaRecruiting
- University of Kansas Cancer CenterKansas City, KansasRecruiting
- University of Kansas Hospital-Westwood Cancer CenterWestwood, KansasRecruiting
- University of New Mexico Cancer CenterAlbuquerque, New MexicoRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Pittsburgh, PennsylvaniaRecruiting
- University of Tennessee - KnoxvilleKnoxville, TennesseeRecruiting
- UPMC Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC HorizonFarrell, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - New CastleNew Castle, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint MargaretPittsburgh, PennsylvaniaRecruiting
- UPMC-Shadyside HospitalPittsburgh, PennsylvaniaRecruiting
- VCU Massey Cancer Center at Stony PointRichmond, VirginiaRecruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
- Wake Forest University Health SciencesWinston-Salem, North CarolinaRecruiting
- Wayne State University/Karmanos Cancer InstituteDetroit, MichiganRecruiting
- Weisberg Cancer Treatment CenterFarmington Hills, MichiganRecruiting
- WellSpan Health-York Cancer CenterYork, PennsylvaniaRecruiting
- Zablocki Veterans Administration Medical CenterMilwaukee, WisconsinRecruiting
- Keck Medicine of USC Buena ParkBuena Park, CaliforniaSuspended
- Los Angeles General Medical CenterLos Angeles, CaliforniaSuspended
- ProHealth D N Greenwald CenterMukwonago, WisconsinActive Not Recruiting
- ProHealth Oconomowoc Memorial HospitalOconomowoc, WisconsinActive Not Recruiting
- USC / Norris Comprehensive Cancer CenterLos Angeles, CaliforniaSuspended
- USC Norris Oncology/Hematology-Newport BeachNewport Beach, CaliforniaSuspended
- UW Cancer Center at ProHealth CareWaukesha, WisconsinActive Not Recruiting
Who to ask about joining
Site Public Contact480-278-8261penny.labriola@arizonaccc.com
Site Public Contact623-773-2873
Site Public Contact412-339-5294Roster@nrgoncology.org
Site Public Contact870-936-7066Emily.Carvell@bmhcc.org
Who can join
This study is open to adults aged 18 and older who are set to receive radiation and chemotherapy with cisplatin for head and neck cancer. Patients need to have specific types of squamous cell carcinoma and must not have certain health issues. The trial team will confirm who is eligible to participate.
What happens during the trial
Participants will be randomly placed into one of two groups. One group will receive BMX-001 along with their usual treatment. The other group will receive a placebo, which is an inactive substance, instead of BMX-001. Everyone will also get standard care to manage side effects. Participants will have regular check-ups and may provide blood samples during the study.
The trial team
The trial is sponsored by NRG Oncology. Dr. David M Brizel is the principal investigator leading the study.
Important dates
The trial started on June 23, 2025, and is expected to finish by January 1, 2027. It is currently recruiting new participants.
Additional information
The trial's ID number is NCT06532279. It is a Phase 2 trial, which means it is looking at how well the treatment works and how safe it is. The study is FDA-regulated and aims to include about 98 participants.
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