Improving Outcomes for High-Risk Head and Neck Cancer with New Treatment Combinations
NCT01810913 · RecruitingAbout this trial
This trial looks at how well radiation therapy works when combined with different chemotherapy options and an immunotherapy drug after surgery in patients with high-risk head and neck cancer. The main goal is to find out if new treatment combinations can improve outcomes compared to the usual treatment. This includes comparing the effects of different drug combinations on the cancer.
Locations and contact
This trial is running at 342 locations in 3 countries. 221 of them are currently recruiting.
United States338 locations · 221 recruiting
- Adena Regional Medical CenterChillicothe, OhioRecruiting
- AdventHealth ParkerParker, ColoradoRecruiting
- AdventHealth PorterDenver, ColoradoRecruiting
- Alegent Health Bergan Mercy Medical CenterOmaha, NebraskaRecruiting
- Allegheny General HospitalPittsburgh, PennsylvaniaRecruiting
- Allegiance HealthJackson, MichiganRecruiting
- Aspirus Cancer Care - Wisconsin RapidsWisconsin Rapids, WisconsinRecruiting
- Aspirus Cancer Care-Antigo-Volm Cancer CenterAntigo, WisconsinRecruiting
- Aspirus Cancer Care-Rhinelander-James Beck Cancer CenterRhinelander, WisconsinRecruiting
- Aspirus Cancer Care-WausauWausau, WisconsinRecruiting
- Atrium Health Cabarrus/LCI-ConcordConcord, North CarolinaRecruiting
- Atrium Health Pineville/LCI-PinevilleCharlotte, North CarolinaRecruiting
- Atrium Health Stanly/LCI-AlbemarleAlbemarle, North CarolinaRecruiting
- Atrium Health Union/LCI-UnionMonroe, North CarolinaRecruiting
- Atrium Health University City/LCI-UniversityCharlotte, North CarolinaRecruiting
- Augusta University Medical CenterAugusta, GeorgiaRecruiting
- Banner University Medical Center - TucsonTucson, ArizonaRecruiting
- Boston Medical CenterBoston, MassachusettsRecruiting
- Camden Clark Medical CenterParkersburg, West VirginiaRecruiting
- Cancer Center of Western WisconsinNew Richmond, WisconsinRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carlisle Regional Cancer CenterCarlisle, PennsylvaniaRecruiting
- Carolinas Medical Center/Levine Cancer InstituteCharlotte, North CarolinaRecruiting
- Case Western Reserve UniversityCleveland, OhioRecruiting
- Cedars-Sinai Medical CenterLos Angeles, CaliforniaRecruiting
- Central Maryland Radiation Oncology in Howard CountyColumbia, MarylandRecruiting
- CHI Health Good SamaritanKearney, NebraskaRecruiting
- Clackamas Radiation Oncology CenterClackamas, OregonRecruiting
- Cleveland Clinic Cancer Center StrongsvilleStrongsville, OhioRecruiting
- Cleveland Clinic FoundationCleveland, OhioRecruiting
- Cleveland Clinic Wooster Family Health and Surgery CenterWooster, OhioRecruiting
- Coborn Cancer Center at Saint Cloud HospitalSaint Cloud, MinnesotaRecruiting
- Community Medical CenterToms River, New JerseyRecruiting
- Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, MichiganRecruiting
- CoxHealth South HospitalSpringfield, MissouriRecruiting
- Crossroads Cancer CenterEffingham, IllinoisRecruiting
- Dartmouth Cancer Center - NorthSaint Johnsbury, VermontRecruiting
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
- Decatur Memorial HospitalDecatur, IllinoisRecruiting
- Drexel Town Square Health CenterOak Creek, WisconsinRecruiting
- ECU Health Oncology KinstonKinston, North CarolinaRecruiting
- Emory University Hospital MidtownAtlanta, GeorgiaRecruiting
- Emory University Hospital/Winship Cancer InstituteAtlanta, GeorgiaRecruiting
- Fox Chase Cancer CenterPhiladelphia, PennsylvaniaRecruiting
- Froedtert Menomonee Falls HospitalMenomonee Falls, WisconsinRecruiting
- Froedtert West Bend Hospital/Kraemer Cancer CenterWest Bend, WisconsinRecruiting
- Geauga HospitalChardon, OhioRecruiting
- George Washington University Medical CenterWashington D.C., District of ColumbiaRecruiting
- Gibbs Cancer Center-PelhamGreer, South CarolinaRecruiting
- Greater Baltimore Medical CenterBaltimore, MarylandRecruiting
- Hennepin County Medical CenterMinneapolis, MinnesotaRecruiting
- Henry Ford Cancer Institute-DownriverBrownstown, MichiganRecruiting
- Henry Ford HospitalDetroit, MichiganRecruiting
- Henry Ford Macomb Hospital-Clinton TownshipClinton Township, MichiganRecruiting
- Henry Ford Medical Center-ColumbusNovi, MichiganRecruiting
- Henry Ford Medical Center-FairlaneDearborn, MichiganRecruiting
- Henry Ford West Bloomfield HospitalWest Bloomfield, MichiganRecruiting
- Henry Ford Wyandotte HospitalWyandotte, MichiganRecruiting
- Highland HospitalRochester, New YorkRecruiting
- Holy Cross HospitalFort Lauderdale, FloridaRecruiting
- HSHS Saint Elizabeth's HospitalO'Fallon, IllinoisRecruiting
- Huntsman Cancer Institute/University of UtahSalt Lake City, UtahRecruiting
- IRMC Cancer CenterIndiana, PennsylvaniaRecruiting
- John H Stroger Jr Hospital of Cook CountyChicago, IllinoisRecruiting
- Johns Hopkins University/Sidney Kimmel Cancer CenterBaltimore, MarylandRecruiting
- Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, New YorkRecruiting
- Lawrence Memorial HospitalLawrence, KansasRecruiting
- Lehigh Valley Hospital - MuhlenbergBethlehem, PennsylvaniaRecruiting
- Lehigh Valley Hospital-Cedar CrestAllentown, PennsylvaniaRecruiting
- Longmont United HospitalLongmont, ColoradoRecruiting
- LSU Health Baton Rouge-North ClinicBaton Rouge, LouisianaRecruiting
- Mayo Clinic in RochesterRochester, MinnesotaRecruiting
- Medical College of WisconsinMilwaukee, WisconsinRecruiting
- Medical University of South CarolinaCharleston, South CarolinaRecruiting
- Memorial Health University Medical CenterSavannah, GeorgiaRecruiting
- Memorial Medical CenterModesto, CaliforniaRecruiting
- Memorial Sloan Kettering Basking RidgeBasking Ridge, New JerseyRecruiting
- Memorial Sloan Kettering BergenMontvale, New JerseyRecruiting
- Memorial Sloan Kettering Cancer CenterNew York, New YorkRecruiting
- Memorial Sloan Kettering CommackCommack, New YorkRecruiting
- Memorial Sloan Kettering MonmouthMiddletown, New JerseyRecruiting
- Memorial Sloan Kettering NassauUniondale, New YorkRecruiting
- Memorial Sloan Kettering WestchesterHarrison, New YorkRecruiting
- Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
- Mercy Hospital SpringfieldSpringfield, MissouriRecruiting
- Mercy San Juan Medical CenterCarmichael, CaliforniaRecruiting
- Miller-Dwan HospitalDuluth, MinnesotaRecruiting
- Mills Health CenterSan Mateo, CaliforniaRecruiting
- Minnesota Oncology - BurnsvilleBurnsville, MinnesotaRecruiting
- Missouri Baptist Medical CenterSt Louis, MissouriRecruiting
- Moffitt Cancer CenterTampa, FloridaRecruiting
- Moffitt Cancer Center at SouthShoreRuskin, FloridaRecruiting
- Moffitt Cancer Center-International PlazaTampa, FloridaRecruiting
- Monmouth Medical CenterLong Branch, New JerseyRecruiting
- Montefiore Medical Center - Moses CampusThe Bronx, New YorkRecruiting
- Montefiore Medical Center-Einstein CampusThe Bronx, New YorkRecruiting
- Mount Sinai Union SquareNew York, New YorkRecruiting
- MyMichigan Medical Center SaginawSaginaw, MichiganRecruiting
- New Mexico Oncology Hematology ConsultantsAlbuquerque, New MexicoRecruiting
- North Memorial Medical Health CenterRobbinsdale, MinnesotaRecruiting
- NorthShore University HealthSystem-Evanston HospitalEvanston, IllinoisRecruiting
- NorthShore University HealthSystem-Glenbrook HospitalGlenview, IllinoisRecruiting
- NorthShore University HealthSystem-Highland Park HospitalHighland Park, IllinoisRecruiting
- NYU Langone Hospital - Long IslandMineola, New YorkRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- Orlando Health Cancer InstituteOrlando, FloridaRecruiting
- OSF Saint Francis Medical CenterPeoria, IllinoisRecruiting
- OSF Saint Francis Radiation Oncology at Peoria Cancer CenterPeoria, IllinoisRecruiting
- Our Lady of the Lake Physician GroupBaton Rouge, LouisianaRecruiting
- PeaceHealth Saint John Medical CenterLongview, WashingtonRecruiting
- Penrose-Saint Francis HealthcareColorado Springs, ColoradoRecruiting
- Phelps Health Delbert Day Cancer InstituteRolla, MissouriRecruiting
- Pocono Medical CenterEast Stroudsburg, PennsylvaniaRecruiting
- Prisma Health Cancer Institute - EastsideGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - FarisGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - GreerGreer, South CarolinaRecruiting
- Prisma Health Cancer Institute - SenecaSeneca, South CarolinaRecruiting
- Providence Portland Medical CenterPortland, OregonRecruiting
- Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, CaliforniaRecruiting
- Providence Saint Vincent Medical CenterPortland, OregonRecruiting
- Robert Wood Johnson University Hospital SomersetSomerville, New JerseyRecruiting
- Rock Hill Radiation Therapy CenterRock Hill, South CarolinaRecruiting
- Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
- Rutgers New Jersey Medical SchoolNewark, New JerseyRecruiting
- Saint Alphonsus Cancer Care Center-NampaNampa, IdahoRecruiting
- Saint Barnabas Medical CenterLivingston, New JerseyRecruiting
- Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
- Saint Luke's Cancer Center - AllentownAllentown, PennsylvaniaRecruiting
- Saint Luke's Hospital - Monroe CampusStroudsburg, PennsylvaniaRecruiting
- Saint Luke's Hospital - Upper Bucks CampusQuakertown, PennsylvaniaRecruiting
- Saint Luke's Hospital-Anderson CampusEaston, PennsylvaniaRecruiting
- Salina Regional Health CenterSalina, KansasRecruiting
- Sands Cancer CenterCanandaigua, New YorkRecruiting
- Sanford Bismarck Medical CenterBismarck, North DakotaRecruiting
- Sanford Joe Lueken Cancer CenterBemidji, MinnesotaRecruiting
- Sanford Roger Maris Cancer CenterFargo, North DakotaRecruiting
- Sanford USD Medical Center - Sioux FallsSioux Falls, South DakotaRecruiting
- Shaw Cancer CenterEdwards, ColoradoRecruiting
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, MissouriRecruiting
- Siteman Cancer Center at West County HospitalCreve Coeur, MissouriRecruiting
- Skagit Regional Health Cancer Care CenterMount Vernon, WashingtonRecruiting
- Smilow Cancer Hospital Care Center - WaterfordWaterford, ConnecticutRecruiting
- Southern Ohio Medical CenterPortsmouth, OhioRecruiting
- Spartanburg Medical CenterSpartanburg, South CarolinaRecruiting
- Springfield Memorial HospitalSpringfield, IllinoisRecruiting
- Stanford Cancer Institute Palo AltoPalo Alto, CaliforniaRecruiting
- State University of New York Upstate Medical UniversitySyracuse, New YorkRecruiting
- Sutter Cancer Centers Radiation Oncology Services-AuburnAuburn, CaliforniaRecruiting
- Sutter Cancer Centers Radiation Oncology Services-Cameron ParkCameron Park, CaliforniaRecruiting
- Sutter Cancer Centers Radiation Oncology Services-RosevilleRoseville, CaliforniaRecruiting
- Sutter Medical Center SacramentoSacramento, CaliforniaRecruiting
- Temple University HospitalPhiladelphia, PennsylvaniaRecruiting
- The Cancer Institute of New Jersey HamiltonHamilton, New JerseyRecruiting
- The James Graham Brown Cancer Center at University of LouisvilleLouisville, KentuckyRecruiting
- The University of Kansas Cancer Center - OlatheOlathe, KansasRecruiting
- Thomas Jefferson University HospitalPhiladelphia, PennsylvaniaRecruiting
- Touro InfirmaryNew Orleans, LouisianaRecruiting
- Trinity Health Medical Center - BrightonBrighton, MichiganRecruiting
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, MichiganRecruiting
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, MichiganRecruiting
- UH Seidman Cancer Center at Firelands Regional Medical CenterSandusky, OhioRecruiting
- UH Seidman Cancer Center at Lake Health Mentor CampusMentor, OhioRecruiting
- UH Seidman Cancer Center at Southwest General HospitalMiddleburg Heights, OhioRecruiting
- UH Seidman Cancer Center at UH Avon Health CenterAvon, OhioRecruiting
- UHHS-Chagrin Highlands Medical CenterBeachwood, OhioRecruiting
- UHHS-Westlake Medical CenterWestlake, OhioRecruiting
- UM Baltimore Washington Medical Center/Tate Cancer CenterGlen Burnie, MarylandRecruiting
- UM Upper Chesapeake Medical CenterBel Air, MarylandRecruiting
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, North CarolinaRecruiting
- University Hospitals Parma Medical CenterParma, OhioRecruiting
- University Hospitals Portage Medical CenterRavenna, OhioRecruiting
- University Medical Center New OrleansNew Orleans, LouisianaRecruiting
- University of Arizona Cancer Center-North CampusTucson, ArizonaRecruiting
- University of Kansas Cancer CenterKansas City, KansasRecruiting
- University of Kansas Cancer Center - Lee's SummitLee's Summit, MissouriRecruiting
- University of Kansas Cancer Center - NorthKansas City, MissouriRecruiting
- University of Kansas Cancer Center-Overland ParkOverland Park, KansasRecruiting
- University of Maryland/Greenebaum Cancer CenterBaltimore, MarylandRecruiting
- University of Michigan Health - Sparrow LansingLansing, MichiganRecruiting
- University of Michigan Health - WestWyoming, MichiganRecruiting
- University of New Mexico Cancer CenterAlbuquerque, New MexicoRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of RochesterRochester, New YorkRecruiting
- University of Washington Medical Center - MontlakeSeattle, WashingtonRecruiting
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - Johnson CreekJohnson Creek, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
- UofL Health Medical Center NortheastLouisville, KentuckyRecruiting
- UPMC AltoonaAltoona, PennsylvaniaRecruiting
- UPMC Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC HorizonFarrell, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC McKeesportMcKeesport, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC NorthwestSeneca, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center in CoraopolisMoon Township, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC Uniontown Hospital Radiation OncologyUniontown, PennsylvaniaRecruiting
- UPMC Washington Hospital Radiation OncologyWashington, PennsylvaniaRecruiting
- UPMC-Heritage Valley Health System BeaverBeaver, PennsylvaniaRecruiting
- UPMC-Johnstown/John P. Murtha Regional Cancer CenterJohnstown, PennsylvaniaRecruiting
- UPMC-Magee Womens HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint MargaretPittsburgh, PennsylvaniaRecruiting
- UPMC-Shadyside HospitalPittsburgh, PennsylvaniaRecruiting
- UT MD Anderson - League CityLeague City, TexasRecruiting
- UT MD Anderson - Sugar LandSugar Land, TexasRecruiting
- UT MD Anderson - The WoodlandsConroe, TexasRecruiting
- UT MD Anderson - West HoustonHouston, TexasRecruiting
- UT MD Anderson Cancer CenterHouston, TexasRecruiting
- UW Health Carbone Cancer Center RockfordRockford, IllinoisRecruiting
- Washington University School of MedicineSt Louis, MissouriRecruiting
- Wenatchee Valley Hospital and ClinicsWenatchee, WashingtonRecruiting
- West Michigan Cancer CenterKalamazoo, MichiganRecruiting
- West Virginia University HealthcareMorgantown, West VirginiaRecruiting
- Wexford Health and Wellness PavilionWexford, PennsylvaniaRecruiting
- Wheeling Hospital/Schiffler Cancer CenterWheeling, West VirginiaRecruiting
- Wilmot Cancer Institute Radiation Oncology at GreeceRochester, New YorkRecruiting
- Yale UniversityNew Haven, ConnecticutRecruiting
- AdventHealth OrlandoOrlando, FloridaActive Not Recruiting
- Advocate Christ Medical CenterOak Lawn, IllinoisActive Not Recruiting
- AnMed Health Cancer CenterAnderson, South CarolinaSuspended
- Arnot Ogden Medical Center/Falck Cancer CenterElmira, New YorkSuspended
- Ascension Saint Vincent AndersonAnderson, IndianaActive Not Recruiting
- Aspirus Cancer Care - Stevens PointStevens Point, WisconsinActive Not Recruiting
- Banner North Colorado Medical CenterGreeley, ColoradoSuspended
- Banner North Colorado Medical Center - Loveland CampusLoveland, ColoradoSuspended
- Bay Area Medical CenterMarinette, WisconsinActive Not Recruiting
- Christiana Care Health System-Christiana HospitalNewark, DelawareSuspended
- Cleveland Clinic Akron GeneralAkron, OhioActive Not Recruiting
- Cleveland Clinic Cancer Center IndependenceIndependence, OhioSuspended
- Cleveland Clinic Cancer Center/Fairview HospitalCleveland, OhioActive Not Recruiting
- Corewell Health Beaumont Troy HospitalTroy, MichiganActive Not Recruiting
- Corewell Health William Beaumont University HospitalRoyal Oak, MichiganActive Not Recruiting
- Covenant Medical Center-LakesideLubbock, TexasActive Not Recruiting
- East Carolina UniversityGreenville, North CarolinaSuspended
- Elkhart General HospitalElkhart, IndianaActive Not Recruiting
- Goshen Center for Cancer CareGoshen, IndianaActive Not Recruiting
- Gundersen Lutheran Medical CenterLa Crosse, WisconsinActive Not Recruiting
- Helen F Graham Cancer CenterNewark, DelawareSuspended
- Hillcrest Hospital Cancer CenterMayfield Heights, OhioActive Not Recruiting
- Holy Cross HospitalSilver Spring, MarylandActive Not Recruiting
- Indiana University/Melvin and Bren Simon Cancer CenterIndianapolis, IndianaSuspended
- Inova Fairfax HospitalFalls Church, VirginiaActive Not Recruiting
- Intermountain Medical CenterMurray, UtahActive Not Recruiting
- Iowa Methodist Medical CenterDes Moines, IowaActive Not Recruiting
- IU Health Central Indiana Cancer Centers-EastIndianapolis, IndianaActive Not Recruiting
- IU Health Methodist HospitalIndianapolis, IndianaSuspended
- Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerSavannah, GeorgiaActive Not Recruiting
- Marshfield Medical CenterMarshfield, WisconsinActive Not Recruiting
- Marshfield Medical Center - MinocquaMinocqua, WisconsinActive Not Recruiting
- Mayo Clinic Health System-Franciscan HealthcareLa Crosse, WisconsinActive Not Recruiting
- McFarland Clinic - AmesAmes, IowaActive Not Recruiting
- Memorial Hospital of South BendSouth Bend, IndianaActive Not Recruiting
- Memorial Sloan Kettering Sleepy HollowSleepy Hollow, New YorkActive Not Recruiting
- Mercy Cancer Center-ElyriaElyria, OhioSuspended
- MetroHealth Medical CenterCleveland, OhioActive Not Recruiting
- Michiana Hematology Oncology PC-MishawakaMishawaka, IndianaActive Not Recruiting
- MU Health - University Hospital/Ellis Fischel Cancer CenterColumbia, MissouriActive Not Recruiting
- Nebraska Methodist HospitalOmaha, NebraskaActive Not Recruiting
- New York-Presbyterian/Brooklyn Methodist HospitalBrooklyn, New YorkSuspended
- North Coast Cancer CareSandusky, OhioActive Not Recruiting
- North Kansas City HospitalKansas City, MissouriSuspended
- Northwell Health/Center for Advanced MedicineLake Success, New YorkActive Not Recruiting
- Northwestern UniversityChicago, IllinoisSuspended
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterNew York, New YorkActive Not Recruiting
- NYU Langone Hospital - BrooklynBrooklyn, New YorkActive Not Recruiting
- Ochsner Medical Center JeffersonNew Orleans, LouisianaActive Not Recruiting
- OhioHealth Mansfield HospitalMansfield, OhioSuspended
- Our Lady of The LakeBaton Rouge, LouisianaSuspended
- Parkview Hospital RandalliaFort Wayne, IndianaActive Not Recruiting
- Parkview Regional Medical CenterFort Wayne, IndianaActive Not Recruiting
- Penn State Milton S Hershey Medical CenterHershey, PennsylvaniaActive Not Recruiting
- Prisma Health Cancer Institute - SpartanburgBoiling Springs, South CarolinaSuspended
- Queen's Medical CenterHonolulu, HawaiiActive Not Recruiting
- Radiation Oncology Associates PCFort Wayne, IndianaSuspended
- Rapid City Regional HospitalRapid City, South DakotaActive Not Recruiting
- Reading HospitalWest Reading, PennsylvaniaSuspended
- Rocky Mountain Cancer Centers-BoulderBoulder, ColoradoActive Not Recruiting
- Rocky Mountain Cancer Centers-LittletonLittleton, ColoradoActive Not Recruiting
- Roswell Park Cancer InstituteBuffalo, New YorkActive Not Recruiting
- Rush MD Anderson Cancer CenterChicago, IllinoisActive Not Recruiting
- Saint Francis HospitalFederal Way, WashingtonSuspended
- Saint George Regional Medical CenterSt. George, UtahActive Not Recruiting
- Saint Helena HospitalSt. Helena, CaliforniaActive Not Recruiting
- Saint Joseph's/Candler - Bluffton CampusBluffton, South CarolinaActive Not Recruiting
- Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, WisconsinActive Not Recruiting
- Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, WisconsinActive Not Recruiting
- Saint Vincent Hospital Cancer Center Green BayGreen Bay, WisconsinActive Not Recruiting
- Sentara Cancer Institute at Sentara CarePlex HospitalHampton, VirginiaActive Not Recruiting
- Sentara Norfolk General HospitalNorfolk, VirginiaActive Not Recruiting
- Sentara Virginia Beach General HospitalVirginia Beach, VirginiaActive Not Recruiting
- Siteman Cancer Center-South CountySt Louis, MissouriActive Not Recruiting
- South Shore University HospitalBay Shore, New YorkActive Not Recruiting
- Sparta Cancer Treatment CenterSparta, New JerseySuspended
- Spokane Valley Cancer Center-MayfairSpokane, WashingtonSuspended
- Spokane Valley Cancer Center-MissionSpokane, WashingtonSuspended
- Summa Health Medina Medical CenterMedina, OhioActive Not Recruiting
- Summa Health System - Akron CampusAkron, OhioActive Not Recruiting
- Summa Health System - Barberton CampusBarberton, OhioActive Not Recruiting
- The Cancer Center of Hawaii-LilihaHonolulu, HawaiiActive Not Recruiting
- The Kirklin Clinic at Acton RoadBirmingham, AlabamaSuspended
- The University of Kansas Cancer Center-SouthKansas City, MissouriSuspended
- Tri-Cities Cancer CenterKennewick, WashingtonSuspended
- Tulane University School of MedicineNew Orleans, LouisianaActive Not Recruiting
- UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, CaliforniaActive Not Recruiting
- UC San Diego Health System - EncinitasEncinitas, CaliforniaSuspended
- UC San Diego Moores Cancer CenterLa Jolla, CaliforniaSuspended
- UCHealth University of Colorado HospitalAurora, ColoradoActive Not Recruiting
- UCSF Medical Center-Mission BaySan Francisco, CaliforniaSuspended
- UCSF Medical Center-Mount ZionSan Francisco, CaliforniaSuspended
- UM Sylvester Comprehensive Cancer Center at Deerfield BeachDeerfield Beach, FloridaActive Not Recruiting
- University of Alabama at Birmingham Cancer CenterBirmingham, AlabamaActive Not Recruiting
- University of Arkansas for Medical SciencesLittle Rock, ArkansasActive Not Recruiting
- University of California Davis Comprehensive Cancer CenterSacramento, CaliforniaSuspended
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, OhioSuspended
- University of Cincinnati Cancer Center-West ChesterWest Chester, OhioSuspended
- University of ConnecticutFarmington, ConnecticutActive Not Recruiting
- University of IllinoisChicago, IllinoisActive Not Recruiting
- University of Kentucky/Markey Cancer CenterLexington, KentuckyActive Not Recruiting
- University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, FloridaActive Not Recruiting
- University of Michigan - Brighton Center for Specialty CareBrighton, MichiganActive Not Recruiting
- University of Michigan Rogel Cancer CenterAnn Arbor, MichiganActive Not Recruiting
- University of Mississippi Medical CenterJackson, MississippiSuspended
- University of Texas Medical BranchGalveston, TexasActive Not Recruiting
- UPMC Cancer Center-Natrona HeightsNatrona Heights, PennsylvaniaSuspended
- UPMC JamesonNew Castle, PennsylvaniaSuspended
- UPMC Jefferson Regional Radiation OncologyPittsburgh, PennsylvaniaSuspended
- UT Southwestern/Simmons Cancer Center-DallasDallas, TexasActive Not Recruiting
- Utah Cancer Specialists-Salt Lake CitySalt Lake City, UtahActive Not Recruiting
- UTMB Cancer Center at Victory LakesLeague City, TexasActive Not Recruiting
- Vanderbilt University/Ingram Cancer CenterNashville, TennesseeActive Not Recruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaActive Not Recruiting
- Virtua MemorialMount Holly, New JerseyActive Not Recruiting
- Virtua VoorheesVoorhees Township, New JerseyActive Not Recruiting
- Wake Forest University Health SciencesWinston-Salem, North CarolinaActive Not Recruiting
Canada3 locations
- Allan Blair Cancer CentreRegina, SaskatchewanSuspended
- Cross Cancer InstituteEdmonton, AlbertaSuspended
- Saskatoon Cancer CentreSaskatoon, SaskatchewanActive Not Recruiting
Hong Kong1 location
- Chinese University of Hong Kong-Prince of Wales HospitalShatinActive Not Recruiting
Who to ask about joining
Site Public ContactUACC-IIT@uacc.arizona.edu
Site Public Contactclinicalresearch@sutterhealth.org
Site Public Contact818-847-4793Najee.Boucher@providence.org
Who can join
Adults aged 18 and older can join this trial. It is open to both men and women who have a specific type of head and neck cancer that has been surgically removed. Some health requirements must be met, and the trial team will check to confirm if someone is eligible.
What happens during the trial
Participants are randomly placed into one of four treatment groups. Everyone will receive radiation therapy, but some will also get different chemotherapy drugs or the immunotherapy drug, atezolizumab. Blood samples and scans may also be done throughout the study to monitor health.
The trial team
The trial is sponsored by the National Cancer Institute (NCI) and involves NRG Oncology. Dr. Paul M Harari is the principal investigator leading the study.
Important dates
The trial started on March 22, 2013, and is currently enrolling participants. It is expected to finish by January 1, 2027.
Additional information
This is a Phase 2 and Phase 3 trial, meaning it is looking at how well the treatments work and their safety. The trial is FDA-regulated, and it aims to include about 613 participants.
Similar trials
Other recruiting trials for the same condition, with the eligibility rules written in plain language.
Browse similar trials →Talk to a specialist
Find a top oncologist who can tell you whether a trial is a sensible option for you.
Find a doctor →Cancer hospitals
The cancer centers running studies like this one, and what each is known for.
Browse hospitals →