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Pairing Healthy Women to Study Early Signs of Ovarian Cancer

NCT06962059 · Recruiting
About this trial

This study looks at how bacteria and their byproducts in the body may help find ovarian cancer early. Researchers will collect vaginal swabs and stool samples from healthy women and compare these to samples from women at higher risk of ovarian cancer. The goal is to understand if these samples can help predict the development of ovarian cancer.

Locations and contact

This trial is running at 1 location in the United States. It is currently recruiting.

United States1 location · 1 recruiting
  • Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PennsylvaniaRecruiting
Who can join

Women aged 30 to 50 who have ovaries can join. They should not have certain genetic mutations that increase cancer risk, a history of cancer or cancer treatment, or have used hormone replacement therapy or antibiotics within the past month. The trial team will confirm who is eligible.

What happens during the trial

Participants will collect vaginal swabs and a stool sample. This is done by the participants themselves. They will be in one group of healthy volunteers who do not have a genetic risk for ovarian cancer. Samples will be collected only once during the study.

The trial team

The trial is sponsored by the Abramson Cancer Center at Penn Medicine. Dr. Susan Domchek from the University of Pennsylvania is the principal investigator.

Important dates

The trial started on April 21, 2025, and is expected to finish by May 25, 2027. It is currently recruiting new participants.

Additional information

The trial's ID number is NCT06962059. This is an observational study, meaning it is looking at how things happen without giving any treatments. It is not regulated by the FDA. The study hopes to include 50 participants.

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