About this trial
This study looks at how bacteria and their byproducts in the body may help find ovarian cancer early. Researchers will collect vaginal swabs and stool samples from healthy women and compare these to samples from women at higher risk of ovarian cancer. The goal is to understand if these samples can help predict the development of ovarian cancer.
The trial's ID number is NCT06962059. This is an observational study, meaning it is looking at how things happen without giving any treatments. It is not regulated by the FDA. The study hopes to include 50 participants.
Who can join
Women aged 30 to 50 who have ovaries can join. They should not have certain genetic mutations that increase cancer risk, a history of cancer or cancer treatment, or have used hormone replacement therapy or antibiotics within the past month. The trial team will confirm who is eligible.
Conditions
Ovarian Cancer, Genetic Predisposition to Disease
The study team makes the final call on eligibility.
What happens in the study
Participants will collect vaginal swabs and a stool sample. This is done by the participants themselves. They will be in one group of healthy volunteers who do not have a genetic risk for ovarian cancer. Samples will be collected only once during the study.
Where
This trial is running at 1 location in the United States. It is currently recruiting.
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania