Studying New Treatment for Prostate Cancer That Returns After Surgery
NCT04423211 · RecruitingAbout this trial
This clinical trial looks at how well a combination of treatments works for men with prostate cancer that has come back after surgery. It compares standard treatment with a new approach that includes a medicine called apalutamide and radiation therapy. The goal is to see if this enhanced treatment helps control cancer better than standard treatment alone, especially for patients whose cancer has spread outside the pelvis.
Locations and contact
This trial is running at 342 locations in the United States. 278 of them are currently recruiting.
United States342 locations · 278 recruiting
- Abbott-Northwestern HospitalMinneapolis, MinnesotaRecruiting
- Alaska Breast Care and Surgery LLCAnchorage, AlaskaRecruiting
- Alaska Oncology and Hematology LLCAnchorage, AlaskaRecruiting
- Alaska Women's Cancer CareAnchorage, AlaskaRecruiting
- Alegent Health Bergan Mercy Medical CenterOmaha, NebraskaRecruiting
- Alton Memorial HospitalAlton, IllinoisRecruiting
- Anchorage Associates in Radiation MedicineAnchorage, AlaskaRecruiting
- Aspirus Cancer Care - James Beck Cancer CenterRhinelander, WisconsinRecruiting
- Aspirus Cancer Care - Stevens PointStevens Point, WisconsinRecruiting
- Aspirus Cancer Care - Wisconsin RapidsWisconsin Rapids, WisconsinRecruiting
- Aspirus Regional Cancer CenterWausau, WisconsinRecruiting
- Baptist Cancer Center-GrenadaGrenada, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-OxfordOxford, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, MississippiRecruiting
- Bay Area HospitalCoos Bay, OregonRecruiting
- Benefis Sletten Cancer InstituteGreat Falls, MontanaRecruiting
- Bethesda North HospitalCincinnati, OhioRecruiting
- Billings Clinic Cancer CenterBillings, MontanaRecruiting
- BJC Outpatient Center at Sunset HillsSunset Hills, MissouriRecruiting
- Bozeman Health Deaconess HospitalBozeman, MontanaRecruiting
- Cancer Care Center of O'FallonO'Fallon, IllinoisRecruiting
- Cancer Care Northwest - Spokane SouthSpokane, WashingtonRecruiting
- Cancer Care Northwest-North SpokaneSpokane, WashingtonRecruiting
- Cancer Care Specialists of Illinois - DecaturDecatur, IllinoisRecruiting
- Cancer Center at Saint Joseph'sPhoenix, ArizonaRecruiting
- Cancer Center of Western WisconsinNew Richmond, WisconsinRecruiting
- Carle at The RiverfrontDanville, IllinoisRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
- Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
- Carlisle Regional Cancer CenterCarlisle, PennsylvaniaRecruiting
- Central Care Cancer Center - BolivarBolivar, MissouriRecruiting
- Central Care Cancer Center - Garden CityGarden City, KansasRecruiting
- Centralia Oncology ClinicCentralia, IllinoisRecruiting
- CHI Health Good SamaritanKearney, NebraskaRecruiting
- City of Hope Antelope ValleyLancaster, CaliforniaRecruiting
- City of Hope Comprehensive Cancer CenterDuarte, CaliforniaRecruiting
- City of Hope CoronaCorona, CaliforniaRecruiting
- City of Hope South PasadenaSouth Pasadena, CaliforniaRecruiting
- City of Hope UplandUpland, CaliforniaRecruiting
- Clackamas Radiation Oncology CenterClackamas, OregonRecruiting
- Coborn Cancer Center at Saint Cloud HospitalSaint Cloud, MinnesotaRecruiting
- Community Medical CenterMissoula, MontanaRecruiting
- Community Medical CenterToms River, New JerseyRecruiting
- Cooper Hospital University Medical CenterCamden, New JerseyRecruiting
- CoxHealth South HospitalSpringfield, MissouriRecruiting
- Creighton University Medical CenterOmaha, NebraskaRecruiting
- Crossroads Cancer CenterEffingham, IllinoisRecruiting
- Decatur Memorial HospitalDecatur, IllinoisRecruiting
- Dillon Health Center/Shaw Cancer CenterDillon, ColoradoRecruiting
- ECU Health Oncology KinstonKinston, North CarolinaRecruiting
- Fairview Clinics and Surgery Center Maple GroveMaple Grove, MinnesotaRecruiting
- Fairview Southdale HospitalEdina, MinnesotaRecruiting
- FHCC at Northwest HospitalSeattle, WashingtonRecruiting
- Fred Hutchinson Cancer CenterSeattle, WashingtonRecruiting
- Freeman Health SystemJoplin, MissouriRecruiting
- Good Samaritan Hospital - CincinnatiCincinnati, OhioRecruiting
- Great Falls ClinicGreat Falls, MontanaRecruiting
- Health Partners IncMinneapolis, MinnesotaRecruiting
- Heartland Regional Medical CenterSaint Joseph, MissouriRecruiting
- Hennepin County Medical CenterMinneapolis, MinnesotaRecruiting
- Hi-Line Sletten Cancer CenterHavre, MontanaRecruiting
- HSHS Saint Elizabeth's HospitalO'Fallon, IllinoisRecruiting
- Illinois CancerCare - WashingtonWashington, IllinoisRecruiting
- Illinois CancerCare-BloomingtonBloomington, IllinoisRecruiting
- Illinois CancerCare-CantonCanton, IllinoisRecruiting
- Illinois CancerCare-CarthageCarthage, IllinoisRecruiting
- Illinois CancerCare-EurekaEureka, IllinoisRecruiting
- Illinois CancerCare-GalesburgGalesburg, IllinoisRecruiting
- Illinois CancerCare-Kewanee ClinicKewanee, IllinoisRecruiting
- Illinois CancerCare-MacombMacomb, IllinoisRecruiting
- Illinois CancerCare-Ottawa ClinicOttawa, IllinoisRecruiting
- Illinois CancerCare-PekinPekin, IllinoisRecruiting
- Illinois CancerCare-PeoriaPeoria, IllinoisRecruiting
- Illinois CancerCare-PeruPeru, IllinoisRecruiting
- Illinois CancerCare-PrincetonPrinceton, IllinoisRecruiting
- Johns Hopkins University/Sidney Kimmel Cancer CenterBaltimore, MarylandRecruiting
- Kadlec Clinic Hematology and OncologyKennewick, WashingtonRecruiting
- Katmai Oncology GroupAnchorage, AlaskaRecruiting
- Kootenai Clinic Cancer Services - Post FallsPost Falls, IdahoRecruiting
- Kootenai Health - Coeur d'AleneCoeur d'Alene, IdahoRecruiting
- Lake Regional HospitalOsage Beach, MissouriRecruiting
- Lakeview HospitalStillwater, MinnesotaRecruiting
- Langlade Hospital and Cancer CenterAntigo, WisconsinRecruiting
- Lenox Hill HospitalNew York, New YorkRecruiting
- Logan Health Medical CenterKalispell, MontanaRecruiting
- Longmont United HospitalLongmont, ColoradoRecruiting
- LSU Health Baton Rouge-North ClinicBaton Rouge, LouisianaRecruiting
- Manhattan Eye Ear and Throat HospitalNew York, New YorkRecruiting
- Marshfield Medical Center - MinocquaMinocqua, WisconsinRecruiting
- Marshfield Medical Center - WestonWeston, WisconsinRecruiting
- Marshfield Medical Center-EC Cancer CenterEau Claire, WisconsinRecruiting
- Marshfield Medical Center-MarshfieldMarshfield, WisconsinRecruiting
- Marshfield Medical Center-Rice LakeRice Lake, WisconsinRecruiting
- Marshfield Medical Center-River Region at Stevens PointStevens Point, WisconsinRecruiting
- MD Anderson Cancer Center at Cooper-VoorheesVoorhees Township, New JerseyRecruiting
- Medical University of South CarolinaCharleston, South CarolinaRecruiting
- Memorial Hospital of CarbondaleCarbondale, IllinoisRecruiting
- Memorial Hospital of Laramie CountyCheyenne, WyomingRecruiting
- Mercy Cancer Center - Cape GirardeauCape Girardeau, MissouriRecruiting
- Mercy Cancer Center - CarmichaelCarmichael, CaliforniaRecruiting
- Mercy Cancer Center - Elk GroveElk Grove, CaliforniaRecruiting
- Mercy Cancer Center - RocklinRocklin, CaliforniaRecruiting
- Mercy Cancer Center - SacramentoSacramento, CaliforniaRecruiting
- Mercy Clinic-Rolla-Cancer and HematologyRolla, MissouriRecruiting
- Mercy HospitalCedar Rapids, IowaRecruiting
- Mercy HospitalCoon Rapids, MinnesotaRecruiting
- Mercy Hospital Fort SmithFort Smith, ArkansasRecruiting
- Mercy Hospital JoplinJoplin, MissouriRecruiting
- Mercy Hospital Oklahoma CityOklahoma City, OklahomaRecruiting
- Mercy Hospital PittsburgPittsburg, KansasRecruiting
- Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
- Mercy Hospital SouthSt Louis, MissouriRecruiting
- Mercy Hospital SpringfieldSpringfield, MissouriRecruiting
- Mercy San Juan Medical CenterCarmichael, CaliforniaRecruiting
- Methodist Medical Center of IllinoisPeoria, IllinoisRecruiting
- Minnesota Oncology - BurnsvilleBurnsville, MinnesotaRecruiting
- Minnesota Oncology - Coon RapidsCoon Rapids, MinnesotaRecruiting
- Minnesota Oncology - EdinaEdina, MinnesotaRecruiting
- Minnesota Oncology - Maple GroveMaple Grove, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-ChaskaChaska, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-MaplewoodMaplewood, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-WoodburyWoodbury, MinnesotaRecruiting
- Mission Hope Medical Oncology - Arroyo GrandeArroyo Grande, CaliforniaRecruiting
- Mission Hope Medical Oncology - Santa MariaSanta Maria, CaliforniaRecruiting
- Missouri Baptist Medical CenterSt Louis, MissouriRecruiting
- Missouri Baptist Sullivan HospitalSullivan, MissouriRecruiting
- Moffitt Cancer CenterTampa, FloridaRecruiting
- Moffitt Cancer Center - McKinley CampusTampa, FloridaRecruiting
- Moffitt Cancer Center at Wesley ChapelWesley Chapel, FloridaRecruiting
- Moffitt Cancer Center-International PlazaTampa, FloridaRecruiting
- Montefiore Medical Center - Moses CampusThe Bronx, New YorkRecruiting
- Montefiore Medical Center-Einstein CampusThe Bronx, New YorkRecruiting
- Montefiore Medical Center-Weiler HospitalThe Bronx, New YorkRecruiting
- Monticello Cancer CenterMonticello, MinnesotaRecruiting
- Mount Sinai ChelseaNew York, New YorkRecruiting
- Mount Sinai HospitalNew York, New YorkRecruiting
- Mount Sinai Union SquareNew York, New YorkRecruiting
- Mount Sinai WestNew York, New YorkRecruiting
- New York Proton CenterNew York, New YorkRecruiting
- North Memorial Medical Health CenterRobbinsdale, MinnesotaRecruiting
- Northwell Health Imbert Cancer CenterBay Shore, New YorkRecruiting
- Northwell Health Physicians Partners Radiation Medicine at QueensForest Hills, New YorkRecruiting
- Northwell Health/Center for Advanced MedicineLake Success, New YorkRecruiting
- Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
- Northwestern Medicine Oak BrookOak Brook, IllinoisRecruiting
- Northwestern UniversityChicago, IllinoisRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- Oncology Associates at Mercy Medical CenterCedar Rapids, IowaRecruiting
- Oregon Health and Science UniversityPortland, OregonRecruiting
- OSF Saint Anthony's Health CenterAlton, IllinoisRecruiting
- Our Lady of the Lake Physician GroupBaton Rouge, LouisianaRecruiting
- Pacific Central Coast Health Center-San Luis ObispoSan Luis Obispo, CaliforniaRecruiting
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, MinnesotaRecruiting
- Parkland Health Center - FarmingtonFarmington, MissouriRecruiting
- Parkland Memorial HospitalDallas, TexasRecruiting
- PeaceHealth Saint John Medical CenterLongview, WashingtonRecruiting
- PeaceHealth Saint Joseph Medical CenterBellingham, WashingtonRecruiting
- PeaceHealth Southwest Medical CenterVancouver, WashingtonRecruiting
- PeaceHealth United General Medical CenterSedro-Woolley, WashingtonRecruiting
- Penn Presbyterian Medical CenterPhiladelphia, PennsylvaniaRecruiting
- Penn State Milton S Hershey Medical CenterHershey, PennsylvaniaRecruiting
- Penrose-Saint Francis HealthcareColorado Springs, ColoradoRecruiting
- Phelps Health Delbert Day Cancer InstituteRolla, MissouriRecruiting
- Phelps Memorial Hospital CenterSleepy Hollow, New YorkRecruiting
- Providence Alaska Medical CenterAnchorage, AlaskaRecruiting
- Providence Newberg Medical CenterNewberg, OregonRecruiting
- Providence Portland Medical CenterPortland, OregonRecruiting
- Providence Regional Cancer PartnershipEverett, WashingtonRecruiting
- Providence Regional Cancer System-AberdeenAberdeen, WashingtonRecruiting
- Providence Regional Cancer System-CentraliaCentralia, WashingtonRecruiting
- Providence Regional Cancer System-LaceyLacey, WashingtonRecruiting
- Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, CaliforniaRecruiting
- Providence Saint Mary Regional Cancer CenterWalla Walla, WashingtonRecruiting
- Providence Saint Vincent Medical CenterPortland, OregonRecruiting
- Providence Willamette Falls Medical CenterOregon City, OregonRecruiting
- Queens Cancer CenterRego Park, New YorkRecruiting
- Regions HospitalSaint Paul, MinnesotaRecruiting
- Rice Memorial HospitalWillmar, MinnesotaRecruiting
- Ridgeview Medical CenterWaconia, MinnesotaRecruiting
- Robert Wood Johnson University Hospital SomersetSomerville, New JerseyRecruiting
- Rocky Mountain Cancer Centers-PenroseColorado Springs, ColoradoRecruiting
- Rush MD Anderson Cancer CenterChicago, IllinoisRecruiting
- Rush MD Anderson Cancer Center at Rush LisleLisle, IllinoisRecruiting
- Rush MD Anderson Cancer Center at Rush Oak ParkOak Park, IllinoisRecruiting
- Rush-Copley Medical CenterAurora, IllinoisRecruiting
- Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
- Saint Anthony HospitalLakewood, ColoradoRecruiting
- Saint Anthony North HospitalWestminster, ColoradoRecruiting
- Saint Charles Health SystemBend, OregonRecruiting
- Saint Francis Cancer CenterColorado Springs, ColoradoRecruiting
- Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
- Saint Francis Regional Medical CenterShakopee, MinnesotaRecruiting
- Saint John's Hospital - HealtheastMaplewood, MinnesotaRecruiting
- Saint Joseph HospitalLexington, KentuckyRecruiting
- Saint Joseph Hospital EastLexington, KentuckyRecruiting
- Saint Joseph Radiation Oncology Resource CenterLexington, KentuckyRecruiting
- Saint Joseph's Medical CenterStockton, CaliforniaRecruiting
- Saint Luke's Cancer Institute - BoiseBoise, IdahoRecruiting
- Saint Luke's Cancer Institute - FruitlandFruitland, IdahoRecruiting
- Saint Luke's Cancer Institute - MeridianMeridian, IdahoRecruiting
- Saint Luke's Cancer Institute - NampaNampa, IdahoRecruiting
- Saint Luke's Cancer Institute - Twin FallsTwin Falls, IdahoRecruiting
- Saint Mary Corwin Medical CenterPueblo, ColoradoRecruiting
- Saint Michael Cancer CenterSilverdale, WashingtonRecruiting
- Saint Patrick Hospital - Community HospitalMissoula, MontanaRecruiting
- Sainte Genevieve County Memorial HospitalSainte Genevieve, MissouriRecruiting
- Shaw Cancer CenterEdwards, ColoradoRecruiting
- Sibley Memorial HospitalWashington D.C., District of ColumbiaRecruiting
- SIH Cancer InstituteCarterville, IllinoisRecruiting
- Siteman Cancer Center at Christian HospitalSt Louis, MissouriRecruiting
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, MissouriRecruiting
- Siteman Cancer Center at West County HospitalCreve Coeur, MissouriRecruiting
- Siteman Cancer Center-South CountySt Louis, MissouriRecruiting
- Skagit Regional Health Cancer Care CenterMount Vernon, WashingtonRecruiting
- Southern Illinois University School of MedicineSpringfield, IllinoisRecruiting
- Springfield ClinicSpringfield, IllinoisRecruiting
- Springfield Memorial HospitalSpringfield, IllinoisRecruiting
- SSM Health Good SamaritanMount Vernon, IllinoisRecruiting
- Stony Brook University Medical CenterStony Brook, New YorkRecruiting
- Suburban HospitalBethesda, MarylandRecruiting
- Swedish Cancer Institute-EdmondsEdmonds, WashingtonRecruiting
- Swedish Cancer Institute-IssaquahIssaquah, WashingtonRecruiting
- Swedish Medical Center-Ballard CampusSeattle, WashingtonRecruiting
- Swedish Medical Center-Cherry HillSeattle, WashingtonRecruiting
- Swedish Medical Center-First HillSeattle, WashingtonRecruiting
- Tarrant County Hospital District/JPS Health NetworkFort Worth, TexasRecruiting
- The Carle Foundation HospitalUrbana, IllinoisRecruiting
- Thomas Jefferson University HospitalPhiladelphia, PennsylvaniaRecruiting
- UC San Diego Health System - EncinitasEncinitas, CaliforniaRecruiting
- UC San Diego Medical Center - HillcrestSan Diego, CaliforniaRecruiting
- UC San Diego Moores Cancer CenterLa Jolla, CaliforniaRecruiting
- UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, CaliforniaRecruiting
- United HospitalSaint Paul, MinnesotaRecruiting
- University of IllinoisChicago, IllinoisRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of Pennsylvania/Abramson Cancer CenterPhiladelphia, PennsylvaniaRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Pittsburgh, PennsylvaniaRecruiting
- University of Virginia Cancer CenterCharlottesville, VirginiaRecruiting
- University of Washington Medical Center - MontlakeSeattle, WashingtonRecruiting
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - Johnson CreekJohnson Creek, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
- UPMC AltoonaAltoona, PennsylvaniaRecruiting
- UPMC Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC HorizonFarrell, PennsylvaniaRecruiting
- UPMC Cancer Center at UPMC NorthwestSeneca, PennsylvaniaRecruiting
- UPMC Cancer Center-Natrona HeightsNatrona Heights, PennsylvaniaRecruiting
- UPMC Cancer Center-UniontownUniontown, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - New CastleNew Castle, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center in CoraopolisMoon Township, PennsylvaniaRecruiting
- UPMC MemorialYork, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC SusquehannaWilliamsport, PennsylvaniaRecruiting
- UPMC Uniontown Hospital Radiation OncologyUniontown, PennsylvaniaRecruiting
- UPMC Washington Hospital Radiation OncologyWashington, PennsylvaniaRecruiting
- UPMC-Heritage Valley Health System BeaverBeaver, PennsylvaniaRecruiting
- UPMC-Johnstown/John P. Murtha Regional Cancer CenterJohnstown, PennsylvaniaRecruiting
- UPMC-Magee Womens HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint MargaretPittsburgh, PennsylvaniaRecruiting
- UPMC-Shadyside HospitalPittsburgh, PennsylvaniaRecruiting
- UT Southwestern Clinical Center at Richardson/PlanoRichardson, TexasRecruiting
- UT Southwestern Simmons Cancer Center - RedBirdDallas, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-DallasDallas, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, TexasRecruiting
- UW Health Carbone Cancer Center RockfordRockford, IllinoisRecruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
- Washington University School of MedicineSt Louis, MissouriRecruiting
- Westchester Medical CenterValhalla, New YorkRecruiting
- William S Middleton VA Medical CenterMadison, WisconsinRecruiting
- Woodland Memorial HospitalWoodland, CaliforniaRecruiting
- AdventHealth LittletonLittleton, ColoradoSuspended
- AdventHealth ParkerParker, ColoradoSuspended
- AdventHealth PorterDenver, ColoradoSuspended
- Alegent Health Immanuel Medical CenterOmaha, NebraskaSuspended
- Alegent Health Lakeside HospitalOmaha, NebraskaSuspended
- Anchorage Oncology CentreAnchorage, AlaskaSuspended
- Audie L Murphy VA HospitalSan Antonio, TexasActive Not Recruiting
- BASS Medical Group - LennonWalnut Creek, CaliforniaActive Not Recruiting
- Central Care Cancer Center - Great BendGreat Bend, KansasSuspended
- Crozer Regional Cancer Center at Brinton LakeGlen Mills, PennsylvaniaActive Not Recruiting
- Crozer-Keystone Regional Cancer Center at BroomallBroomall, PennsylvaniaActive Not Recruiting
- Delaware County Memorial HospitalDrexel Hill, PennsylvaniaActive Not Recruiting
- ECU Health Oncology KenansvilleKenansville, North CarolinaSuspended
- ECU Health Oncology RichlandsRichlands, North CarolinaSuspended
- Fairbanks Memorial HospitalFairbanks, AlaskaSuspended
- Fox Chase Cancer CenterPhiladelphia, PennsylvaniaActive Not Recruiting
- Fox Chase Cancer Center - East Norriton Hospital Outpatient CenterEast Norriton, PennsylvaniaActive Not Recruiting
- Fox Chase Cancer Center BuckinghamFurlong, PennsylvaniaActive Not Recruiting
- Hackensack University Medical CenterHackensack, New JerseyActive Not Recruiting
- Idaho Urologic Institute-MeridianMeridian, IdahoSuspended
- Illinois CancerCare-DixonDixon, IllinoisSuspended
- Jewish HospitalLouisville, KentuckySuspended
- Legacy Cancer Institute Medical Oncology and Day TreatmentVancouver, WashingtonActive Not Recruiting
- Legacy Good Samaritan Hospital and Medical CenterPortland, OregonActive Not Recruiting
- Legacy Meridian Park HospitalTualatin, OregonActive Not Recruiting
- Legacy Mount Hood Medical CenterGresham, OregonActive Not Recruiting
- Legacy Salmon Creek HospitalVancouver, WashingtonActive Not Recruiting
- Los Angeles General Medical CenterLos Angeles, CaliforniaActive Not Recruiting
- Loyola University Medical CenterMaywood, IllinoisActive Not Recruiting
- MaineHealth Cancer Care and IV Therapy - SanfordSanford, MaineActive Not Recruiting
- MaineHealth Cancer Care and IV Therapy - South PortlandSouth Portland, MaineActive Not Recruiting
- MaineHealth Cancer Care Center of York CountySanford, MaineActive Not Recruiting
- MaineHealth Coastal Cancer Treatment CenterBath, MaineActive Not Recruiting
- MaineHealth Maine Medical Center - BiddefordBiddeford, MaineActive Not Recruiting
- MaineHealth Maine Medical Center - PortlandPortland, MaineActive Not Recruiting
- MaineHealth Maine Medical Center- ScarboroughScarborough, MaineActive Not Recruiting
- Mercy Cancer CenterMerced, CaliforniaSuspended
- MU Health Care Goldschmidt Cancer CenterJefferson City, MissouriSuspended
- Presbyterian - Saint Lukes Medical Center - Health OneDenver, ColoradoActive Not Recruiting
- Providence Cancer Institute Clackamas ClinicClackamas, OregonSuspended
- Rocky Mountain Cancer Centers-AuroraAurora, ColoradoActive Not Recruiting
- Rocky Mountain Cancer Centers-BoulderBoulder, ColoradoActive Not Recruiting
- Rocky Mountain Cancer Centers-LittletonLittleton, ColoradoActive Not Recruiting
- Rocky Mountain Cancer Centers-ThorntonThornton, ColoradoActive Not Recruiting
- Saint Alphonsus Cancer Care Center-BoiseBoise, IdahoSuspended
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, IdahoSuspended
- Saint Alphonsus Cancer Care Center-NampaNampa, IdahoSuspended
- Saint Mary's HospitalCentralia, IllinoisSuspended
- Sanford Cancer Center Oncology ClinicSioux Falls, South DakotaSuspended
- Sanford USD Medical Center - Sioux FallsSioux Falls, South DakotaSuspended
- Temple University HospitalPhiladelphia, PennsylvaniaActive Not Recruiting
- The Melanoma and Skin Cancer InstituteEnglewood, ColoradoActive Not Recruiting
- UM Baltimore Washington Medical Center/Tate Cancer CenterGlen Burnie, MarylandActive Not Recruiting
- Unity HospitalFridley, MinnesotaActive Not Recruiting
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, OhioActive Not Recruiting
- University of Cincinnati Cancer Center-West ChesterWest Chester, OhioActive Not Recruiting
- University of Maryland/Greenebaum Cancer CenterBaltimore, MarylandActive Not Recruiting
- University of Mississippi Medical CenterJackson, MississippiActive Not Recruiting
- University of Texas Health Science Center at San AntonioSan Antonio, TexasActive Not Recruiting
- USC / Norris Comprehensive Cancer CenterLos Angeles, CaliforniaActive Not Recruiting
- VA Palo Alto Health Care SystemPalo Alto, CaliforniaActive Not Recruiting
- Valley Radiation OncologyPeru, IllinoisSuspended
- Welch Cancer CenterSheridan, WyomingSuspended
- Western Illinois Cancer Treatment CenterGalesburg, IllinoisSuspended
Who to ask about joining
Site Public Contact907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Site Public Contact720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Site Public Contact800-378-9373
Who can join
Men aged 18 and older can join this trial if they have had surgery for prostate cancer and have a rise in a blood test called PSA. Patients must not have any evidence of cancer spread outside the pelvis based on certain imaging tests. The trial team will confirm each person's eligibility before they can participate.
What happens during the trial
Participants will be randomly placed into different groups. Some will receive standard treatment, while others will get the enhanced treatment that includes apalutamide and radiation. Everyone will go through imaging tests to help guide their treatment. The treatments are given over a period of time, and participants will be monitored for their response to the therapies.
The trial team
The trial is sponsored by the ECOG-ACRIN Cancer Research Group, with collaboration from the National Cancer Institute. Dr. Neha Vapiwala is the principal investigator leading this study.
Important dates
The trial started on October 8, 2020, and is currently enrolling new participants. It is expected to finish by December 31, 2032.
Additional information
This is a Phase 3 trial, which means it is looking at how effective the treatments are and how safe they are. The trial is FDA-regulated and aims to include around 804 participants.
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