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Supporting New Treatment Options for Metastatic Pancreatic Cancer Patients

NCT07562152 · Recruiting
About this trial

This study looks at a new treatment for patients with metastatic pancreatic cancer. It compares a combination of atebimetinib with a modified version of gemcitabine and nab-paclitaxel to the standard version of these treatments. The main goal is to see if the new combination helps patients live longer and feel better during treatment.

Locations and contact

This trial is running at 19 locations in 2 countries. All of them are currently recruiting.

United States17 locations · 17 recruiting
  • Blue Ridge Cancer CareBlacksburg, VirginiaRecruiting
  • City of HopePhoenix, ArizonaRecruiting
  • City of HopeDuarte, CaliforniaRecruiting
  • City of HopeChicago, IllinoisRecruiting
  • Comprehensive Cancer CentersLas Vegas, NevadaRecruiting
  • Illinois Cancer SpecialistsArlington Heights, IllinoisRecruiting
  • Missouri Cancer AssociatesColumbia, MissouriRecruiting
  • Northwest Cancer SpecialistsVancouver, WashingtonRecruiting
  • NYU Langone HealthNew York, New YorkRecruiting
  • OSF Medical CenterPeoria, IllinoisRecruiting
  • Piedmont HealthcareAtlanta, GeorgiaRecruiting
  • Regional Cancer CareBelleville, New JerseyRecruiting
  • Sarah Cannon Research InstituteNashville, TennesseeRecruiting
  • Taylor Cancer Research CenterMaumee, OhioRecruiting
  • Texas Oncology - San AntonioSan Antonio, TexasRecruiting
  • Texas Oncology Gulf CoastWebster, TexasRecruiting
  • Thomas Jefferson UniversityPhiladelphia, PennsylvaniaRecruiting
Australia2 locations · 2 recruiting
  • Calvary Mater NewcastleWaratah, New South WalesRecruiting
  • Icon Cancer Centre - ChermsideChermside, QueenslandRecruiting
Who to ask about joining
Who can join

Adults aged 18 and older can join if they have been diagnosed with metastatic pancreatic adenocarcinoma within 12 weeks before starting the study. They should not have received any previous treatment for cancer and must have measurable disease. The trial is open to all genders. The team will confirm who is eligible to participate.

What happens during the trial

Participants will be randomly placed into two groups. One group will receive atebimetinib along with modified gemcitabine and nab-paclitaxel. The other group will receive the standard gemcitabine and nab-paclitaxel. Treatment will include oral tablets and intravenous infusions.

The trial team

The study is sponsored by Immuneering Corporation, which is responsible for running the trial.

Important dates

The trial started in June 2026 and is expected to finish by February 2029. It is currently enrolling new participants.

Additional information

This is a Phase 3 trial, meaning it is looking at how well the treatment works and how safe it is. The trial aims to include about 510 participants, and it is regulated by the FDA.

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