Targeting Side Effects of Cancer Immunotherapy for Better Patient Comfort
NCT06673329 · RecruitingThis study looks at how well brodalumab works to help patients with side effects from cancer immunotherapy. These side effects happen when the immune system is activated after treatment. The goal is to find a safe way to control these side effects and improve patients' comfort. Brodalumab is already used for other conditions where the immune system is active against the body, and researchers hope it can help here too.
Locations and contact
This trial is running at 1 location in the United States. It is currently recruiting.
United States1 location · 1 recruiting
- Columbia University Irving Medical CenterNew York, New YorkRecruiting
Who can join
Adults over 18 years old may join if they have a side effect from cancer treatment that is thought to be caused by the immune system. They must also have had prior treatment with steroids for these side effects. Patients currently being treated with curative intent or who have certain health conditions may not be able to participate. The trial team will confirm eligibility.
What happens during the trial
Participants will receive brodalumab, an injection under the skin, for 24 weeks. They will be monitored closely through visits and check-ups, which may include telemedicine appointments. Everyone will receive the same treatment, and they will have assessments to see how well the treatment is working and if there are any side effects.
The trial team
The trial is led by Dr. Brian Henick from Columbia University. Bausch Health Americas, Inc. is also involved in this study.
Important dates
The trial started on March 11, 2025, and is expected to finish by November 2027. It is currently enrolling new participants.
Additional information
The trial ID is NCT06673329. It is a Phase 1 study, which means researchers are looking at how well the treatment works and its safety. This study is regulated by the FDA, and they hope to include about 11 participants.
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