Tracking New Treatment Approaches for High-Risk Cervical Cancer
NCT07061977 · RecruitingAbout this trial
This trial looks at two ways to treat high-risk cervical cancer that has spread to nearby tissues or lymph nodes. It compares a new approach of giving chemotherapy with a drug called pembrolizumab before standard chemotherapy and radiation treatment. The main goal is to see if this new way helps patients live longer without their cancer getting worse.
Locations and contact
This trial is running at 290 locations in the United States. 282 of them are currently recruiting.
United States290 locations · 282 recruiting
- Allegheny General HospitalPittsburgh, PennsylvaniaRecruiting
- Asplundh Cancer PavilionWillow Grove, PennsylvaniaRecruiting
- Atrium Health Cabarrus/LCI-ConcordConcord, North CarolinaRecruiting
- Atrium Medical Center-Middletown Regional HospitalFranklin, OhioRecruiting
- Aultman Health FoundationCanton, OhioRecruiting
- Avera Cancer InstituteSioux Falls, South DakotaRecruiting
- Beebe Health CampusRehoboth Beach, DelawareRecruiting
- Beebe South Coastal Health CampusMillville, DelawareRecruiting
- Billings Clinic Cancer CenterBillings, MontanaRecruiting
- Bronson Methodist HospitalKalamazoo, MichiganRecruiting
- Broward Health Medical CenterFort Lauderdale, FloridaRecruiting
- Camden Clark Medical CenterParkersburg, West VirginiaRecruiting
- Cancer Care Specialists of Illinois - DecaturDecatur, IllinoisRecruiting
- Capital Health Medical Center-HopewellPennington, New JerseyRecruiting
- Carilion Roanoke Memorial HospitalRoanoke, VirginiaRecruiting
- Carle at The RiverfrontDanville, IllinoisRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
- Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
- Carolinas Medical Center/Levine Cancer InstituteCharlotte, North CarolinaRecruiting
- Case Western Reserve UniversityCleveland, OhioRecruiting
- Chelsea HospitalChelsea, MichiganRecruiting
- City of Hope at Irvine LennarIrvine, CaliforniaRecruiting
- City of Hope Comprehensive Cancer CenterDuarte, CaliforniaRecruiting
- City of Hope CoronaCorona, CaliforniaRecruiting
- City of Hope South PasadenaSouth Pasadena, CaliforniaRecruiting
- City of Hope UplandUpland, CaliforniaRecruiting
- Clackamas Radiation Oncology CenterClackamas, OregonRecruiting
- Cleveland Clinic FoundationCleveland, OhioRecruiting
- Cooper Hospital University Medical CenterCamden, New JerseyRecruiting
- CTCA at Southeastern Regional Medical CenterNewnan, GeorgiaRecruiting
- Danbury HospitalDanbury, ConnecticutRecruiting
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
- Decatur Memorial HospitalDecatur, IllinoisRecruiting
- Duke University Medical CenterDurham, North CarolinaRecruiting
- Duke Women's Cancer Care RaleighRaleigh, North CarolinaRecruiting
- Duluth Clinic AshlandAshland, WisconsinRecruiting
- East Jefferson General HospitalMetairie, LouisianaRecruiting
- Emory Decatur HospitalDecatur, GeorgiaRecruiting
- Emory University Hospital MidtownAtlanta, GeorgiaRecruiting
- Emory University Hospital/Winship Cancer InstituteAtlanta, GeorgiaRecruiting
- Essentia Health - Deer River ClinicDeer River, MinnesotaRecruiting
- Essentia Health Cancer CenterDuluth, MinnesotaRecruiting
- Essentia Health Hibbing ClinicHibbing, MinnesotaRecruiting
- Essentia Health Saint Joseph's Medical CenterBrainerd, MinnesotaRecruiting
- Essentia Health Saint Mary's Hospital - SuperiorSuperior, WisconsinRecruiting
- Essentia Health SandstoneSandstone, MinnesotaRecruiting
- Essentia Health Virginia ClinicVirginia, MinnesotaRecruiting
- Farmington Health CenterFarmington, UtahRecruiting
- Forbes HospitalMonroeville, PennsylvaniaRecruiting
- Fox Chase Cancer CenterPhiladelphia, PennsylvaniaRecruiting
- Freeman Health SystemJoplin, MissouriRecruiting
- Geauga HospitalChardon, OhioRecruiting
- Geisinger Cancer Center Dickson CityDickson City, PennsylvaniaRecruiting
- Geisinger Medical CenterDanville, PennsylvaniaRecruiting
- Geisinger Medical Oncology-LewisburgLewisburg, PennsylvaniaRecruiting
- Geisinger Wyoming Valley/Henry Cancer CenterWilkes-Barre, PennsylvaniaRecruiting
- Gibbs Cancer Center-GaffneyGaffney, South CarolinaRecruiting
- Gibbs Cancer Center-PelhamGreer, South CarolinaRecruiting
- Health CentralOcoee, FloridaRecruiting
- Helen F Graham Cancer CenterNewark, DelawareRecruiting
- Highlands Oncology GroupSpringdale, ArkansasRecruiting
- Highlands Oncology Group - FayettevilleFayetteville, ArkansasRecruiting
- Highlands Oncology Group - RogersRogers, ArkansasRecruiting
- Hillcrest Hospital Cancer CenterMayfield Heights, OhioRecruiting
- Huntsman Cancer Institute/University of UtahSalt Lake City, UtahRecruiting
- Indiana University/Melvin and Bren Simon Cancer CenterIndianapolis, IndianaRecruiting
- Inova Alexandria HospitalAlexandria, VirginiaRecruiting
- Inova Fair Oaks HospitalFairfax, VirginiaRecruiting
- Inova Fairfax HospitalFalls Church, VirginiaRecruiting
- Inova Loudoun HospitalLeesburg, VirginiaRecruiting
- Inova Schar Cancer InstituteFairfax, VirginiaRecruiting
- Iowa Methodist Medical CenterDes Moines, IowaRecruiting
- IRMC Cancer CenterIndiana, PennsylvaniaRecruiting
- IU Health North HospitalCarmel, IndianaRecruiting
- Jefferson HospitalJefferson Hills, PennsylvaniaRecruiting
- Jersey City Medical CenterJersey City, New JerseyRecruiting
- Kaiser Permanente - Panorama CityPanorama City, CaliforniaRecruiting
- Kaiser Permanente Los Angeles Medical CenterLos Angeles, CaliforniaRecruiting
- Kaiser Permanente NorthwestPortland, OregonRecruiting
- Kaiser Permanente South BayHarbor City, CaliforniaRecruiting
- Kaiser Permanente West Los AngelesLos Angeles, CaliforniaRecruiting
- Kaiser Permanente-BellflowerBellflower, CaliforniaRecruiting
- Kaiser Permanente-IrvineIrvine, CaliforniaRecruiting
- Kaiser Permanente-San Diego ZionSan Diego, CaliforniaRecruiting
- Kaiser Permanente-San MarcosSan Marcos, CaliforniaRecruiting
- Kaiser Permanente-Woodland HillsWoodland Hills, CaliforniaRecruiting
- Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, New YorkRecruiting
- Legacy Good Samaritan Hospital and Medical CenterPortland, OregonRecruiting
- Legacy Meridian Park HospitalTualatin, OregonRecruiting
- Legacy Salmon Creek HospitalVancouver, WashingtonRecruiting
- Lehigh Valley Hospital - MuhlenbergBethlehem, PennsylvaniaRecruiting
- Lehigh Valley Hospital-Cedar CrestAllentown, PennsylvaniaRecruiting
- Lenox Hill HospitalNew York, New YorkRecruiting
- Levine Cancer Institute-GastonGastonia, North CarolinaRecruiting
- Loyola University Medical CenterMaywood, IllinoisRecruiting
- LSU Healthcare Network / Metairie Multi-Specialty ClinicMetairie, LouisianaRecruiting
- MaineHealth Cancer Care Center of York CountySanford, MaineRecruiting
- MaineHealth Coastal Cancer Treatment CenterBath, MaineRecruiting
- MaineHealth Maine Medical Center - PortlandPortland, MaineRecruiting
- MaineHealth Maine Medical Center- ScarboroughScarborough, MaineRecruiting
- Manhattan Eye Ear and Throat HospitalNew York, New YorkRecruiting
- Matthews Radiation Oncology CenterMatthews, North CarolinaRecruiting
- Medical College of WisconsinMilwaukee, WisconsinRecruiting
- Medical Oncology Hematology Consultants PANewark, DelawareRecruiting
- Medical University of South CarolinaCharleston, South CarolinaRecruiting
- Memorial Hospital WestPembroke Pines, FloridaRecruiting
- Memorial Regional Hospital/Joe DiMaggio Children's HospitalHollywood, FloridaRecruiting
- Memorial Sloan Kettering Basking RidgeBasking Ridge, New JerseyRecruiting
- Memorial Sloan Kettering BergenMontvale, New JerseyRecruiting
- Memorial Sloan Kettering Cancer CenterNew York, New YorkRecruiting
- Memorial Sloan Kettering CommackCommack, New YorkRecruiting
- Memorial Sloan Kettering MonmouthMiddletown, New JerseyRecruiting
- Memorial Sloan Kettering NassauUniondale, New YorkRecruiting
- Memorial Sloan Kettering WestchesterHarrison, New YorkRecruiting
- Mercy HospitalCedar Rapids, IowaRecruiting
- Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
- Mercy Hospital SpringfieldSpringfield, MissouriRecruiting
- Mercy Medical Center - Des MoinesDes Moines, IowaRecruiting
- Miami Valley Cancer Care and InfusionGreenville, OhioRecruiting
- Miami Valley HospitalDayton, OhioRecruiting
- Miami Valley Hospital NorthDayton, OhioRecruiting
- Miami Valley Hospital SouthCenterville, OhioRecruiting
- Midwestern Regional Medical CenterZion, IllinoisRecruiting
- Miller-Dwan HospitalDuluth, MinnesotaRecruiting
- Moffitt Cancer CenterTampa, FloridaRecruiting
- Moffitt Cancer Center - McKinley CampusTampa, FloridaRecruiting
- Moffitt Cancer Center at SouthShoreRuskin, FloridaRecruiting
- Moffitt Cancer Center at Wesley ChapelWesley Chapel, FloridaRecruiting
- Moffitt Cancer Center-International PlazaTampa, FloridaRecruiting
- Montefiore Medical Center - Moses CampusThe Bronx, New YorkRecruiting
- Montefiore Medical Center-Einstein CampusThe Bronx, New YorkRecruiting
- Mount Sinai ChelseaNew York, New YorkRecruiting
- Mount Sinai HospitalNew York, New YorkRecruiting
- Nebraska Methodist HospitalOmaha, NebraskaRecruiting
- Northern Westchester HospitalMount Kisco, New YorkRecruiting
- Northwell Health Cancer Institute at HuntingtonGreenlawn, New YorkRecruiting
- Northwell Health Imbert Cancer CenterBay Shore, New YorkRecruiting
- Northwell Health Physician Partners at FlushingFlushing, New YorkRecruiting
- Northwell Health Physicians Partners Radiation Medicine at QueensForest Hills, New YorkRecruiting
- Northwell Health/Center for Advanced MedicineLake Success, New YorkRecruiting
- Northwest Cancer Center - Crown PointCrown Point, IndianaRecruiting
- Northwest Cancer Center - HobartHobart, IndianaRecruiting
- Northwest Cancer Center - ValparaisoValparaiso, IndianaRecruiting
- Northwest Oncology LLCDyer, IndianaRecruiting
- Northwest Wisconsin Cancer CenterAshland, WisconsinRecruiting
- Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
- Northwestern Medicine Oak BrookOak Brook, IllinoisRecruiting
- Northwestern Medicine Orland ParkOrland Park, IllinoisRecruiting
- Northwestern UniversityChicago, IllinoisRecruiting
- Norwalk HospitalNorwalk, ConnecticutRecruiting
- Novant Health Cancer Institute - HuntersvilleHuntersville, North CarolinaRecruiting
- Novant Health Forsyth Medical CenterWinston-Salem, North CarolinaRecruiting
- Novant Health Presbyterian Medical CenterCharlotte, North CarolinaRecruiting
- NYU Langone Hospital - Long IslandMineola, New YorkRecruiting
- Ochsner Baptist Medical CenterNew Orleans, LouisianaRecruiting
- Ochsner Medical Center JeffersonNew Orleans, LouisianaRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- Oklahoma Cancer Specialists and Research Institute-TulsaTulsa, OklahomaRecruiting
- Oncology Associates at Mercy Medical CenterCedar Rapids, IowaRecruiting
- Oregon Health and Science UniversityPortland, OregonRecruiting
- Orlando Health Cancer InstituteOrlando, FloridaRecruiting
- OSF Saint Francis Medical CenterPeoria, IllinoisRecruiting
- OSF Saint Francis Radiation Oncology at Peoria Cancer CenterPeoria, IllinoisRecruiting
- Parkland Memorial HospitalDallas, TexasRecruiting
- Parkview Regional Medical CenterFort Wayne, IndianaRecruiting
- Penn State Milton S Hershey Medical CenterHershey, PennsylvaniaRecruiting
- Phelps Health Delbert Day Cancer InstituteRolla, MissouriRecruiting
- Phelps Memorial Hospital CenterSleepy Hollow, New YorkRecruiting
- Piedmont HospitalAtlanta, GeorgiaRecruiting
- Pocono Medical CenterEast Stroudsburg, PennsylvaniaRecruiting
- ProHealth D N Greenwald CenterMukwonago, WisconsinRecruiting
- ProHealth Oconomowoc Memorial HospitalOconomowoc, WisconsinRecruiting
- ProMedica Flower HospitalSylvania, OhioRecruiting
- Providence Newberg Medical CenterNewberg, OregonRecruiting
- Providence Portland Medical CenterPortland, OregonRecruiting
- Providence Saint Vincent Medical CenterPortland, OregonRecruiting
- Providence Willamette Falls Medical CenterOregon City, OregonRecruiting
- Queens Cancer CenterRego Park, New YorkRecruiting
- Roswell Park Cancer InstituteBuffalo, New YorkRecruiting
- Rush MD Anderson Cancer CenterChicago, IllinoisRecruiting
- Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
- Rutgers New Jersey Medical SchoolNewark, New JerseyRecruiting
- Saint Alphonsus Cancer Care Center-BoiseBoise, IdahoRecruiting
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, IdahoRecruiting
- Saint Alphonsus Cancer Care Center-NampaNampa, IdahoRecruiting
- Saint Luke's Cancer Center - AllentownAllentown, PennsylvaniaRecruiting
- Saint Luke's Cancer Institute - BoiseBoise, IdahoRecruiting
- Saint Luke's Cancer Institute - FruitlandFruitland, IdahoRecruiting
- Saint Luke's Cancer Institute - MeridianMeridian, IdahoRecruiting
- Saint Luke's Cancer Institute - NampaNampa, IdahoRecruiting
- Saint Luke's Hospital - Monroe CampusStroudsburg, PennsylvaniaRecruiting
- Saint Luke's Hospital - Upper Bucks CampusQuakertown, PennsylvaniaRecruiting
- Saint Luke's Hospital-Anderson CampusEaston, PennsylvaniaRecruiting
- Saint Luke's University Hospital-Bethlehem CampusBethlehem, PennsylvaniaRecruiting
- Saint Mary Medical CenterHobart, IndianaRecruiting
- Sidney and Lois Eskenazi HospitalIndianapolis, IndianaRecruiting
- Southern Illinois University School of MedicineSpringfield, IllinoisRecruiting
- Spartanburg Medical CenterSpartanburg, South CarolinaRecruiting
- Springfield ClinicSpringfield, IllinoisRecruiting
- Springfield Memorial HospitalSpringfield, IllinoisRecruiting
- State University of New York Upstate Medical UniversitySyracuse, New YorkRecruiting
- Stony Brook University Medical CenterStony Brook, New YorkRecruiting
- Temple University HospitalPhiladelphia, PennsylvaniaRecruiting
- The Community HospitalMunster, IndianaRecruiting
- Thomas Jefferson University HospitalPhiladelphia, PennsylvaniaRecruiting
- Trinity Health Medical Center - BrightonBrighton, MichiganRecruiting
- Trinity Health Medical Center - CantonCanton, MichiganRecruiting
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, MichiganRecruiting
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, MichiganRecruiting
- UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, CaliforniaRecruiting
- UC San Diego Moores Cancer CenterLa Jolla, CaliforniaRecruiting
- UCHealth Highlands Ranch HospitalHighlands Ranch, ColoradoRecruiting
- UCHealth University of Colorado HospitalAurora, ColoradoRecruiting
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, CaliforniaRecruiting
- UH Seidman Cancer Center at Lake Health Mentor CampusMentor, OhioRecruiting
- UH Seidman Cancer Center at Saint John Medical CenterWestlake, OhioRecruiting
- UHHS-Chagrin Highlands Medical CenterBeachwood, OhioRecruiting
- UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, IowaRecruiting
- UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, IowaRecruiting
- UM Sylvester Comprehensive Cancer Center at Coral GablesCoral Gables, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at Coral SpringsCoral Springs, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at Deerfield BeachDeerfield Beach, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at DoralDoral, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at HollywoodHollywood, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at KendallMiami, FloridaRecruiting
- UM Sylvester Comprehensive Cancer Center at PlantationPlantation, FloridaRecruiting
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, North CarolinaRecruiting
- University Hospitals Parma Medical CenterParma, OhioRecruiting
- University Medical Center New OrleansNew Orleans, LouisianaRecruiting
- University of Arkansas for Medical SciencesLittle Rock, ArkansasRecruiting
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, OhioRecruiting
- University of Cincinnati Cancer Center-West ChesterWest Chester, OhioRecruiting
- University of Iowa/Holden Comprehensive Cancer CenterIowa City, IowaRecruiting
- University of Kansas Cancer CenterKansas City, KansasRecruiting
- University of Kansas Cancer Center - BriarcliffKansas City, MissouriRecruiting
- University of Kansas Cancer Center - Lee's SummitLee's Summit, MissouriRecruiting
- University of Kansas Cancer Center - NorthKansas City, MissouriRecruiting
- University of Kansas Cancer Center-Overland ParkOverland Park, KansasRecruiting
- University of Kansas Hospital-Indian Creek CampusOverland Park, KansasRecruiting
- University of Kansas Hospital-Westwood Cancer CenterWestwood, KansasRecruiting
- University of Kentucky/Markey Cancer CenterLexington, KentuckyRecruiting
- University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, FloridaRecruiting
- University of Miami Sylvester Comprehensive Cancer Center at Sole MiaNorth Miami, FloridaRecruiting
- University of Nebraska Medical CenterOmaha, NebraskaRecruiting
- University of New Mexico Cancer CenterAlbuquerque, New MexicoRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of Utah Sugarhouse Health CenterSalt Lake City, UtahRecruiting
- University of Virginia Cancer CenterCharlottesville, VirginiaRecruiting
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
- UPMC Cancer Center at UPMC NorthwestSeneca, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC-Magee Womens HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- Upper Valley Medical CenterTroy, OhioRecruiting
- Upstate Cancer Center at Hill Radiation OncologySyracuse, New YorkRecruiting
- Upstate Cancer Center at VeronaVerona, New YorkRecruiting
- Upstate Cancer Center Radiation Oncology at OswegoOswego, New YorkRecruiting
- UT Southwestern Clinical Center at Richardson/PlanoRichardson, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-DallasDallas, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, TexasRecruiting
- UW Cancer Center at ProHealth CareWaukesha, WisconsinRecruiting
- UW Health Carbone Cancer Center RockfordRockford, IllinoisRecruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
- Wake Forest University Health SciencesWinston-Salem, North CarolinaRecruiting
- West Jefferson Medical CenterMarrero, LouisianaRecruiting
- West Michigan Cancer CenterKalamazoo, MichiganRecruiting
- West Penn HospitalPittsburgh, PennsylvaniaRecruiting
- West Virginia University HealthcareMorgantown, West VirginiaRecruiting
- Wexford Health and Wellness PavilionWexford, PennsylvaniaRecruiting
- Women and Infants HospitalProvidence, Rhode IslandRecruiting
- Women's Cancer Center of NevadaLas Vegas, NevadaRecruiting
- Women's Diagnostic Center - MunsterMunster, IndianaRecruiting
- University of Alabama at Birmingham Cancer CenterBirmingham, AlabamaNot Yet Recruiting
- City of Hope Antelope ValleyLancaster, CaliforniaSuspended
- Community Medical CenterMissoula, MontanaSuspended
- Crossroads Cancer CenterEffingham, IllinoisSuspended
- Kootenai Clinic Cancer Services - Post FallsPost Falls, IdahoSuspended
- Kootenai Health - Coeur d'AleneCoeur d'Alene, IdahoSuspended
- Montefiore Medical Center-Weiler HospitalThe Bronx, New YorkSuspended
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, MichiganSuspended
Who to ask about joining
Site Public Contactgingerreeves@uabmc.edu
Site Public Contact479-872-8100research@hogonc.com
Site Public Contact501-686-8274
Who can join
Women aged 18 and older can join if they have recently been diagnosed with certain types of locally advanced cervical cancer. They should not have had previous major treatments for cervical cancer and should meet specific health criteria. The trial team will confirm if each person is eligible to participate.
What happens during the trial
Participants will be randomly placed into one of two groups. In the first group, patients will receive standard treatment, which includes chemotherapy with a drug called cisplatin, along with radiation therapy and pembrolizumab. In the second group, patients will first receive chemotherapy with carboplatin and paclitaxel, followed by the same standard treatment. Everyone will also have regular health checks with scans throughout the study.
The trial team
The trial is sponsored by the National Cancer Institute (NCI). Dr. Jyoti S Mayadev from NRG Oncology is the principal investigator leading the study.
Important dates
The trial started on November 5, 2025, and is expected to finish by December 31, 2030. It is currently enrolling new participants.
Additional information
The trial's ID number is NCT07061977. This is a Phase 3 trial, which means it is looking at how well the treatment works and how safe it is. The trial is FDA-regulated and hopes to include around 336 participants.
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