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Treating Cancer with MRI: Improving Radiation Therapy Planning

NCT04545957 · Recruiting
About this trial

This study looks at how using MRI can help plan radiation treatments for different types of cancer. It focuses on checking if MRI is a good tool for making radiation treatment plans and if it can improve outcomes for patients. The cancers involved include prostate cancer, liver cancer, head and neck cancer, and recurrent adenocarcinoma.

Locations and contact

This trial is running at 2 locations in the United States. All of them are currently recruiting.

United States2 locations · 2 recruiting
  • Brigham and Women HospitalBoston, MassachusettsRecruiting
  • Dana Farber Cancer InstituteBoston, MassachusettsRecruiting
Who to ask about joining
Who can join

This trial is open to adults aged 18 and older. Both men and women can join if they have a confirmed cancer that needs radiation therapy. Participants must be able to understand the study and sign a consent form. Some people may not be able to join if they have certain allergies to MRI contrast or cannot undergo an MRI.

What happens during the trial

Participants will go through a screening process to see if they are eligible for the study. They will be placed into groups where they will receive different treatment plans using MRI data to help guide radiation therapy. Some will use MRI and synthetic CT together, while others may have adjustments made to their radiation doses based on the MRI results.

The trial team

The trial is led by Brigham and Women's Hospital. Dr. Raymond Mak is the main investigator overseeing the study.

Important dates

The study started on October 14, 2020, and is expected to complete by October 22, 2030. It is currently open for new participants to join.

Additional information

The trial's ID number is NCT04545957. This is a Phase I-II trial, which means it is looking at both the safety and how well this MRI-guided planning works. The FDA regulates the MRI device used in this study. The trial hopes to include about 86 participants.

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