Dr. Lisa D. Yee
Surgical Oncologist · Breast CancerDr. Lisa D. Yee, MD, is a nationally esteemed breast surgical oncologist and translational researcher renowned for her leadership in breast cancer prevention and high‑risk patient care at City of Hope. A graduate of Yale University School of Medicine, she completed her surgical residency at Oregon Health & Science University and Mount Sinai Medical Center (Miami), followed by fellowship training in surgical oncology. Board‑certified in general surgery, Dr. Yee has devoted over three decades to advancing clinical protocols and academic science in breast cancer risk management and survivorship.
Dr. Yee is best known for pioneering clinical trials that investigate nutritional and botanical interventions to reduce breast cancer risk and mitigate treatment side effects. Her research includes studies on omega‑3 fatty acid supplementation in hormone-receptor–negative breast cancer survivors and innovative curcumin formulations to alleviate aromatase inhibitor–induced joint pain. With more than 50 peer-reviewed publications and active involvement in developing prevention-focused frameworks, she has shaped new paradigms in personalized oncology and symptom management.
A dedicated mentor and program leader, Dr. Yee launched a high-risk breast clinic in 1995 and has continuously championed equity and access in cancer prevention research. She trains surgical oncology fellows and collaborates across multidisciplinary teams, integrating precision medicine, population science, and advocacy to optimize outcomes. Through her synergy of surgical skill, research innovation, and compassionate patient care, Dr. Yee continues to lead the evolution of breast cancer prevention and high-risk management.
Education
Medical School:
Yale University School of Medicine
Residency:
General Surgery, Oregon Health Sciences University
General Surgery, Mount Sinai Medical Center
Fellowship:
Surgical Oncology, Mount Sinai Medical Center
Board Certification:
General Surgery
Surgical Oncology
Awards
- 2015, 2016, Top 10 percent of providers nationally for patient satisfaction, Surgical Oncology, The Clinician and Group Consumer Assessment of Healthcare Providers and Systems survey
- Outstanding Achievement in Patient Service 2104, Wexner Medical Center, The Ohio State University
- “Awesome Games Done Quick”–Prevent Cancer Foundation Research Award (White-Button Mushroom Chemoprevention Study
Memberships and affiliations
- Society of Surgical Oncology (SSO)
- American College of Surgeons (ACS)
- American Society of Clinical Oncology (ASCO)
- American Society of Breast Surgeons
- City of Hope National Medical Center
Research and publications
- Metabolic Health, Insulin, and Breast Cancer: Why Oncologists Should Care About Insulin.
- Relationship satisfaction predicts lower stress and inflammation in breast cancer survivors: A longitudinal study of within-person and between-person effects.
- Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.
- The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer.
- Diet Quality, Inflammation, and Quality of Life in Breast Cancer Survivors: A Cross-Sectional Analysis of Pilot Study Data. Journal of the Academy of Nutrition and Dietetics.
- Randomized placebo-controlled pilot trial of omega 3 fatty acids for prevention of aromatase inhibitor-induced musculoskeletal pain.
- Citrus flavonoid naringenin reduces mammary tumor cell viability, adipose mass, and adipose inflammation in obese ovariectomized mice.
- Experiencing the cancer of a loved one influences decision-making for breast cancer prevention.
- Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
- Discovery of stromal regulatory networks that suppress ras-sensitized epithelial cell proliferation.
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