Checking a New Treatment for Women with Advanced Cervical Cancer
NCT06079671 · RecruitingThis study is looking at a new treatment called volrustomig for women with high-risk locally advanced cervical cancer. These patients have not shown any signs of the cancer getting worse after receiving chemotherapy and radiation. The main goal is to see how well volrustomig works and how safe it is for these women.
Locations and contact
This trial is running at 205 locations in 19 countries. 145 of them are currently recruiting.
United States28 locations
- Atlanta, GeorgiaWithdrawn
- Augusta, GeorgiaWithdrawn
- Birmingham, AlabamaWithdrawn
- Charlottesville, VirginiaCompleted
- Cleveland, OhioWithdrawn
- Columbus, OhioWithdrawn
- Dallas, TexasWithdrawn
- Eugene, OregonWithdrawn
- Fairfax, VirginiaWithdrawn
- Fort Worth, TexasTerminated
- Houston, TexasWithdrawn
- Indianapolis, IndianaWithdrawn
- La Jolla, CaliforniaWithdrawn
- Little Rock, ArkansasWithdrawn
- Melrose Park, IllinoisWithdrawn
- New Orleans, LouisianaWithdrawn
- New Orleans, LouisianaWithdrawn
- New York, New YorkWithdrawn
- Philadelphia, PennsylvaniaWithdrawn
- Phoenix, ArizonaWithdrawn
- Providence, Rhode IslandWithdrawn
- Richmond, VirginiaWithdrawn
- Savannah, GeorgiaTerminated
- Shreveport, LouisianaCompleted
- Syracuse, New YorkWithdrawn
- Tucson, ArizonaWithdrawn
- Tyler, TexasWithdrawn
- West Hollywood, CaliforniaWithdrawn
China37 locations · 32 recruiting
- BeijingRecruiting
- BeijingRecruiting
- BeijingRecruiting
- ChangdeRecruiting
- ChangshaRecruiting
- ChangshaRecruiting
- ChengduRecruiting
- ChengduRecruiting
- ChongqingRecruiting
- FuzhouRecruiting
- GanzhouRecruiting
- GuangzhouRecruiting
- HangzhouRecruiting
- HarbinRecruiting
- KunmingRecruiting
- LanzhouRecruiting
- LanzhouRecruiting
- LinyiRecruiting
- NanchangRecruiting
- NanchangRecruiting
- ShanghaiRecruiting
- ShanghaiRecruiting
- ShenyangRecruiting
- ShenzhenRecruiting
- ShenzhenRecruiting
- TianjinRecruiting
- WuhanRecruiting
- WuhanRecruiting
- Xi'anRecruiting
- YinchuanRecruiting
- ZhengzhouRecruiting
- ZhuzhouRecruiting
- GuangzhouWithdrawn
- LuzhouWithdrawn
- ShandongWithdrawn
- YibinWithdrawn
- ZhengzhouTerminated
Japan17 locations · 15 recruiting
- FukuokaRecruiting
- Ginowan-shiRecruiting
- Hidaka-shiRecruiting
- KagoshimaRecruiting
- KōtokuRecruiting
- Kurume-shiRecruiting
- MaebashiRecruiting
- MatsuyamaRecruiting
- MoriokaRecruiting
- NagoyaRecruiting
- SapporoRecruiting
- Shinjuku-kuRecruiting
- Suita-shiRecruiting
- Sunto-gunRecruiting
- Toon-ShiRecruiting
- OsakaWithdrawn
- SapporoWithdrawn
Brazil19 locations · 14 recruiting
- BarretosRecruiting
- Belo HorizonteRecruiting
- CuritibaRecruiting
- FortalezaRecruiting
- NatalRecruiting
- Porto AlegreRecruiting
- Porto AlegreRecruiting
- Porto VelhoRecruiting
- RecifeRecruiting
- Rio de JaneiroRecruiting
- SalvadorRecruiting
- São PauloRecruiting
- São PauloRecruiting
- TeresinaRecruiting
- FortalezaNot Yet Recruiting
- GoiâniaNot Yet Recruiting
- IjuíNot Yet Recruiting
- Porto AlegreNot Yet Recruiting
- São PauloNot Yet Recruiting
Italy13 locations · 11 recruiting
- BolognaRecruiting
- CataniaRecruiting
- FlorenceRecruiting
- MilanRecruiting
- MilanRecruiting
- MilanRecruiting
- MonzaRecruiting
- NaplesRecruiting
- RomaRecruiting
- RomeRecruiting
- TurinRecruiting
- BariWithdrawn
- LeccoCompleted
Spain13 locations · 10 recruiting
- A CoruñaRecruiting
- BarcelonaRecruiting
- BarcelonaRecruiting
- CórdobaRecruiting
- GironaRecruiting
- Hospitalet deLlobregatRecruiting
- MadridRecruiting
- MadridRecruiting
- MadridRecruiting
- ValenciaRecruiting
- MadridWithdrawn
- Palma de MallorcaWithdrawn
- ValenciaWithdrawn
Taiwan10 locations · 10 recruiting
- ChanghuaRecruiting
- Kaohsiung CityRecruiting
- Kaohsiung CityRecruiting
- New Taipei CityRecruiting
- TaichungRecruiting
- TaichungRecruiting
- TainanRecruiting
- TaipeiRecruiting
- TaipeiRecruiting
- TaoyuanRecruiting
India10 locations · 7 recruiting
- JaipurRecruiting
- MaduraiRecruiting
- NagpurRecruiting
- NashikRecruiting
- NashikRecruiting
- New DelhiRecruiting
- VadodaraRecruiting
- CalicutTerminated
- LucknowWithdrawn
- MohaliWithdrawn
South Korea7 locations · 7 recruiting
- DaeguRecruiting
- Goyang-siRecruiting
- Gyeonggi-doRecruiting
- SeoulRecruiting
- SeoulRecruiting
- SeoulRecruiting
- SeoulRecruiting
Peru7 locations · 6 recruiting
- LimaRecruiting
- LimaRecruiting
- LimaRecruiting
- LimaRecruiting
- LimaRecruiting
- LimaRecruiting
- ConcepciónTerminated
Mexico8 locations · 5 recruiting
- CoyoacánRecruiting
- GuadalajaraRecruiting
- MéxicoRecruiting
- Mexico CityRecruiting
- MonterreyRecruiting
- CuliacánWithdrawn
- GuadalajraWithdrawn
- MéxicoWithdrawn
Poland8 locations · 5 recruiting
- BialystokRecruiting
- GdanskRecruiting
- GliwiceRecruiting
- PoznanRecruiting
- WroclawRecruiting
- KrakowWithdrawn
- LodzWithdrawn
- WarsawWithdrawn
Canada7 locations · 5 recruiting
- Hamilton, OntarioRecruiting
- Montreal, QuebecRecruiting
- Montreal, QuebecRecruiting
- Toronto, OntarioRecruiting
- Toronto, OntarioRecruiting
- London, OntarioWithdrawn
- Ste-Foy, QuebecWithdrawn
Thailand5 locations · 5 recruiting
- BangkokRecruiting
- BangkokRecruiting
- BangkokRecruiting
- MuangRecruiting
- Udon ThaniRecruiting
Turkey (Türkiye)6 locations · 4 recruiting
- AdanaRecruiting
- AnkaraRecruiting
- AnkaraRecruiting
- CordaleoRecruiting
- IstanbulWithdrawn
- IstanbulWithdrawn
Germany4 locations · 4 recruiting
- BerlinRecruiting
- BonnRecruiting
- HamburgRecruiting
- LeipzigRecruiting
Denmark3 locations · 3 recruiting
- Aarhus NRecruiting
- København ØRecruiting
- OdenseRecruiting
Norway2 locations · 2 recruiting
- OsloRecruiting
- TrondheimRecruiting
Puerto Rico1 location
- San JuanWithdrawn
Who can join
Women aged 15 years and older can join the study. They must have a specific type of locally advanced cervical cancer and should not have seen their cancer get worse after treatment. The trial team will check to make sure each person meets the requirements before they can participate.
What happens during the trial
Participants will be randomly assigned to one of two groups. One group will receive volrustomig through an IV infusion, and the other group will receive a placebo, which looks like the treatment but has no active medicine. This way, researchers can compare the effects of volrustomig to that of the placebo.
The trial team
The trial is sponsored by AstraZeneca, and it has partners including the Gynecologic Oncology Group Foundation and the European Network of Gynaecological Oncological Trial Groups.
Important dates
The study started on September 22, 2023, and is currently enrolling new participants. It is expected to be completed by September 30, 2030.
Additional information
This is a Phase 3 trial, meaning it is looking closely at how well the treatment works and its safety. The trial aims to include about 800 participants. It is regulated by the FDA.
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