About this trial
This trial looks at how two types of surgery treat lung cancer in patients with osteosarcoma. One method is called thoracotomy, which uses a larger cut to remove cancer. The other method is called thoracoscopy, which uses small cuts and a camera. The main goal is to see which surgery helps patients live longer without cancer returning.
The trial ID is NCT05235165. This is a Phase 3 trial, meaning it looks at how well the treatment works and its safety. It is not for a drug but is regulated by the FDA. The trial hopes to include 62 participants.
Who can join
Men and women under 50 years old can join. They need to have a diagnosis of osteosarcoma and lung nodules that can be removed by surgery. Patients must be in good health and have completed certain treatments before joining. The trial team will confirm eligibility.
Conditions
Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma, Osteosarcoma
The study team makes the final call on eligibility.
What happens in the study
Participants will be randomly placed into one of two groups. In Arm A, they will have open thoracic surgery. In Arm B, they will have thoracoscopy. Everyone will have CT scans during the trial. They may also provide tissue and blood samples for further study.
Where
This trial is running at 219 locations in the United States. 211 of them are currently recruiting.
Albany Medical Center
Albany, New York
Alfred I duPont Hospital for Children
Wilmington, Delaware
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada
Arkansas Children's Hospital
Little Rock, Arkansas
Arnold Palmer Hospital for Children
Orlando, Florida
Banner Children's at Desert
Mesa, Arizona
Banner University Medical Center - Tucson
Tucson, Arizona
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas
The first 8 of 219 sites are listed here. The registry record has the full list.