This study looks at how different programs can help reduce fatigue in women with advanced breast cancer. The programs include prolonged overnight fasting alone, exercise alone, a combination of both, or general health education sessions. The goal is to see which approach helps women feel better while they are receiving certain cancer treatments.
The trial's ID number is NCT06123988. It is not FDA-regulated and hopes to include around 260 participants.
Who can join
This trial is for women aged 18 and older who can understand English or Spanish. Participants must have advanced breast cancer that is hormone receptor positive. They should not have exercised much in the past three months or regularly fasted for 12 hours overnight. The trial team will check to see who can join.
Conditions
HER2-positive Breast Cancer, Advanced Breast Cancer
Age group
Adult, Older adult
Sex
Female
The study team makes the final call on eligibility.
What happens in the study
Participants will be placed into one of four groups by chance. One group will fast overnight, another will exercise, a third will do both, and the last group will attend health education sessions. All groups will complete health surveys and provide blood samples over about 12 months.
Where
This trial is enrolling at 3 locations. Recruiting sites are listed first.
Medical OncologistMedical Oncologist · New York, NY · New York · NY
Director of the Breast Cancer Center at NYU Langone’s Perlmutter Cancer Center. Treats breast cancer. Based in New York. The main cancer doctor for adults. Manages your treatment and your care team. Recognized at state, national or international level. Chosen on merit.
Inaugural Jeffrey F. Moley Professor of Endocrine and Oncologic Surgery, WashU. Treats breast cancer. Works as a surgical oncologist. Based in St. Louis, Missouri. Chosen on merit.
Microsurgical breast reconstruction specialist, MSK. Treats breast cancer and mouth cancer. Offers microsurgical breast reconstruction, head and neck reconstruction and abdominal wall reconstruction. Works as a plastic & reconstructive surgeon. Based in New York. Chosen on merit.