Supporting Immunotherapy to Improve Chemotherapy for Stage II-III Breast Cancer
NCT06058377 · RecruitingAbout this trial
This trial looks at adding an immunotherapy drug called durvalumab to standard chemotherapy for women with certain types of stage II-III breast cancer. The goal is to see if this combination can help improve outcomes for patients. The study focuses on those with hormone receptor positive and HER2 negative breast cancer who are at higher risk of recurrence. Researchers hope that adding durvalumab can help the immune system fight the cancer better.
Locations and contact
This trial is running at 541 locations in 2 countries. 527 of them are currently recruiting.
United States539 locations · 525 recruiting
- Abbott-Northwestern HospitalMinneapolis, MinnesotaRecruiting
- Addison Gilbert HospitalGloucester, MassachusettsRecruiting
- Advocate Christ Medical CenterOak Lawn, IllinoisRecruiting
- Advocate Good Samaritan HospitalDowners Grove, IllinoisRecruiting
- Advocate Good Shepherd HospitalBarrington, IllinoisRecruiting
- Advocate Illinois Masonic Medical CenterChicago, IllinoisRecruiting
- Advocate Lutheran General HospitalPark Ridge, IllinoisRecruiting
- Advocate Outpatient Center - AuroraAurora, IllinoisRecruiting
- Advocate Sherman HospitalElgin, IllinoisRecruiting
- Advocate South Suburban HospitalHazel Crest, IllinoisRecruiting
- AIS Cancer Center at San Joaquin Community HospitalBakersfield, CaliforniaRecruiting
- Allegheny General HospitalPittsburgh, PennsylvaniaRecruiting
- Allegiance HealthJackson, MichiganRecruiting
- Alta Bates Summit Medical Center-Herrick CampusBerkeley, CaliforniaRecruiting
- AMG Crystal Lake - OncologyCrystal Lake, IllinoisRecruiting
- AMG Libertyville - OncologyLibertyville, IllinoisRecruiting
- Arnold Palmer Cancer Center Medical Oncology NorwinN. Huntingdon, PennsylvaniaRecruiting
- Atrium Medical Center-Middletown Regional HospitalFranklin, OhioRecruiting
- Aurora Bay Area Medical Group-MarinetteMarinette, WisconsinRecruiting
- Aurora BayCare Medical CenterGreen Bay, WisconsinRecruiting
- Aurora Cancer Care-GraftonGrafton, WisconsinRecruiting
- Aurora Cancer Care-Kenosha SouthKenosha, WisconsinRecruiting
- Aurora Cancer Care-MilwaukeeMilwaukee, WisconsinRecruiting
- Aurora Cancer Care-Milwaukee WestWauwatosa, WisconsinRecruiting
- Aurora Cancer Care-RacineRacine, WisconsinRecruiting
- Aurora Cancer Care-Southern Lakes VLCCBurlington, WisconsinRecruiting
- Aurora Health Care Germantown Health CenterGermantown, WisconsinRecruiting
- Aurora Medical Center in SummitSummit, WisconsinRecruiting
- Aurora Saint Luke's Medical CenterMilwaukee, WisconsinRecruiting
- Aurora Saint Luke's South ShoreCudahy, WisconsinRecruiting
- Aurora Sinai Medical CenterMilwaukee, WisconsinRecruiting
- Aurora West Allis Medical CenterWest Allis, WisconsinRecruiting
- Banner University Medical Center - TucsonTucson, ArizonaRecruiting
- Baptist Cancer Center-GrenadaGrenada, MississippiRecruiting
- Baptist Health CorbinCorbin, KentuckyRecruiting
- Baptist Memorial Hospital and Cancer Center-ColliervilleCollierville, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-DesotoSouthhaven, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Golden TriangleColumbus, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-MemphisMemphis, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-OxfordOxford, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, MississippiRecruiting
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer CenterHouston, TexasRecruiting
- Beebe Health CampusRehoboth Beach, DelawareRecruiting
- Beebe South Coastal Health CampusMillville, DelawareRecruiting
- Bellin Memorial HospitalGreen Bay, WisconsinRecruiting
- Ben Taub General HospitalHouston, TexasRecruiting
- Benefis Sletten Cancer InstituteGreat Falls, MontanaRecruiting
- Beverly HospitalBeverly, MassachusettsRecruiting
- Billings Clinic Cancer CenterBillings, MontanaRecruiting
- BJC Outpatient Center at Sunset HillsSunset Hills, MissouriRecruiting
- Bon Secours Memorial Regional Medical CenterMechanicsville, VirginiaRecruiting
- Bon Secours Saint Francis HospitalCharleston, South CarolinaRecruiting
- Bon Secours Saint Francis Medical CenterMidlothian, VirginiaRecruiting
- Bon Secours Saint Mary's HospitalRichmond, VirginiaRecruiting
- Bozeman Health Deaconess HospitalBozeman, MontanaRecruiting
- Broadlawns Medical CenterDes Moines, IowaRecruiting
- Bronson Battle CreekBattle Creek, MichiganRecruiting
- Bronson Methodist HospitalKalamazoo, MichiganRecruiting
- Bryn Mawr HospitalBryn Mawr, PennsylvaniaRecruiting
- California Pacific Medical Center-Pacific CampusSan Francisco, CaliforniaRecruiting
- Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, MichiganRecruiting
- Cancer Care and Hematology-Fort CollinsFort Collins, ColoradoRecruiting
- Cancer Care Center of O'FallonO'Fallon, IllinoisRecruiting
- Cancer Care Specialists of Illinois - DecaturDecatur, IllinoisRecruiting
- Cancer Hematology Centers - FlintFlint, MichiganRecruiting
- Carle at The RiverfrontDanville, IllinoisRecruiting
- Carle BroMenn Medical CenterNormal, IllinoisRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carle Cancer Institute NormalNormal, IllinoisRecruiting
- Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
- Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
- Cedars-Sinai Cancer - TarzanaTarzana, CaliforniaRecruiting
- Cedars-Sinai Medical CenterLos Angeles, CaliforniaRecruiting
- Charleston Oncology - RoperCharleston, South CarolinaRecruiting
- Charleston Oncology - Saint FrancisCharleston, South CarolinaRecruiting
- Chelsea HospitalChelsea, MichiganRecruiting
- Chilton Medical CenterPompton, New JerseyRecruiting
- City of Hope Antelope ValleyLancaster, CaliforniaRecruiting
- City of Hope at Irvine LennarIrvine, CaliforniaRecruiting
- City of Hope at Long Beach ElmLong Beach, CaliforniaRecruiting
- City of Hope Comprehensive Cancer CenterDuarte, CaliforniaRecruiting
- City of Hope Newport BeachNewport Beach, CaliforniaRecruiting
- City of Hope South BayTorrance, CaliforniaRecruiting
- City of Hope South PasadenaSouth Pasadena, CaliforniaRecruiting
- City of Hope UplandUpland, CaliforniaRecruiting
- Columbus Oncology and Hematology AssociatesDublin, OhioRecruiting
- Columbus Oncology and Hematology Associates IncColumbus, OhioRecruiting
- CommonSpirit Saint Joseph Medical Center - East LexingtonLexington, KentuckyRecruiting
- Community Hospital of AnacondaAnaconda, MontanaRecruiting
- Community Medical CenterMissoula, MontanaRecruiting
- Community Medical CenterToms River, New JerseyRecruiting
- Community Medical CenterScranton, PennsylvaniaRecruiting
- Condell Memorial HospitalLibertyville, IllinoisRecruiting
- Corewell Health Beaumont Troy HospitalTroy, MichiganRecruiting
- Corewell Health Dearborn HospitalDearborn, MichiganRecruiting
- Corewell Health Farmington Hills HospitalFarmington Hills, MichiganRecruiting
- Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Niles HospitalNiles, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Saint Joseph HospitalSaint Joseph, MichiganRecruiting
- Corewell Health Reed City HospitalReed City, MichiganRecruiting
- Corewell Health William Beaumont University HospitalRoyal Oak, MichiganRecruiting
- Covenant Health Cancer CentersKnoxville, TennesseeRecruiting
- Covenant Health Cancer Centers - WestKnoxville, TennesseeRecruiting
- Covenant Health Oncology Group - Oak RidgeOak Ridge, TennesseeRecruiting
- CoxHealth South HospitalSpringfield, MissouriRecruiting
- Crossroads Cancer CenterEffingham, IllinoisRecruiting
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
- Decatur Memorial HospitalDecatur, IllinoisRecruiting
- Delaware Health Center-Grady Cancer CenterDelaware, OhioRecruiting
- Desert Regional Medical CenterPalm Springs, CaliforniaRecruiting
- Dickstein Cancer Treatment CenterWhite Plains, New YorkRecruiting
- Divine Providence HospitalWilliamsport, PennsylvaniaRecruiting
- Doctors HospitalColumbus, OhioRecruiting
- Drexel Town Square Health CenterOak Creek, WisconsinRecruiting
- Dublin Methodist HospitalDublin, OhioRecruiting
- Duluth Clinic AshlandAshland, WisconsinRecruiting
- Emory Decatur HospitalDecatur, GeorgiaRecruiting
- Emory Johns Creek HospitalJohns Creek, GeorgiaRecruiting
- Emory Saint Joseph's HospitalAtlanta, GeorgiaRecruiting
- Emory University Hospital MidtownAtlanta, GeorgiaRecruiting
- Emory University Hospital/Winship Cancer InstituteAtlanta, GeorgiaRecruiting
- Essentia Health - Deer River ClinicDeer River, MinnesotaRecruiting
- Essentia Health Cancer CenterDuluth, MinnesotaRecruiting
- Essentia Health Cancer Center-South University ClinicFargo, North DakotaRecruiting
- Essentia Health Hibbing ClinicHibbing, MinnesotaRecruiting
- Essentia Health Saint Joseph's Medical CenterBrainerd, MinnesotaRecruiting
- Essentia Health SandstoneSandstone, MinnesotaRecruiting
- Essentia Health Virginia ClinicVirginia, MinnesotaRecruiting
- Essentia Health-Spooner ClinicSpooner, WisconsinRecruiting
- Fairview Southdale HospitalEdina, MinnesotaRecruiting
- Forbes HospitalMonroeville, PennsylvaniaRecruiting
- Froedtert Menomonee Falls HospitalMenomonee Falls, WisconsinRecruiting
- Froedtert West Bend Hospital/Kraemer Cancer CenterWest Bend, WisconsinRecruiting
- Geisinger Cancer Center Dickson CityDickson City, PennsylvaniaRecruiting
- Geisinger Medical CenterDanville, PennsylvaniaRecruiting
- Geisinger Medical Oncology-LewisburgLewisburg, PennsylvaniaRecruiting
- Geisinger Wyoming Valley/Henry Cancer CenterWilkes-Barre, PennsylvaniaRecruiting
- Genesys Hurley Cancer InstituteFlint, MichiganRecruiting
- Good Samaritan University HospitalWest Islip, New YorkRecruiting
- Grady Health SystemAtlanta, GeorgiaRecruiting
- Grady Memorial HospitalDelaware, OhioRecruiting
- Grant Medical CenterColumbus, OhioRecruiting
- Hackettstown Medical CenterHackettstown, New JerseyRecruiting
- HaysMedHays, KansasRecruiting
- Helen F Graham Cancer CenterNewark, DelawareRecruiting
- Hematology Oncology Associates of Fredericksburg IncFredericksburg, VirginiaRecruiting
- Hennepin County Medical CenterMinneapolis, MinnesotaRecruiting
- Henry Ford Cancer Institute-DownriverBrownstown, MichiganRecruiting
- Henry Ford Health Providence Novi HospitalNovi, MichiganRecruiting
- Henry Ford Health Providence Southfield HospitalSouthfield, MichiganRecruiting
- Henry Ford Health Saint John HospitalDetroit, MichiganRecruiting
- Henry Ford Health Warren HospitalWarren, MichiganRecruiting
- Henry Ford HospitalDetroit, MichiganRecruiting
- Henry Ford Macomb Hospital-Clinton TownshipClinton Township, MichiganRecruiting
- Henry Ford Medical Center-ColumbusNovi, MichiganRecruiting
- Henry Ford Medical Center-FairlaneDearborn, MichiganRecruiting
- Henry Ford River District HospitalEast China Township, MichiganRecruiting
- Henry Ford Saint John Hospital - Macomb MedicalMacomb, MichiganRecruiting
- Henry Ford Saint John Hospital - Van ElslanderGrosse Pointe Woods, MichiganRecruiting
- Henry Ford Warren Hospital - GLCMSWarren, MichiganRecruiting
- Henry Ford West Bloomfield HospitalWest Bloomfield, MichiganRecruiting
- Henry Ford Wyandotte HospitalWyandotte, MichiganRecruiting
- Huntington Memorial HospitalPasadena, CaliforniaRecruiting
- Hurley Medical CenterFlint, MichiganRecruiting
- Huron Gastroenterology PCYpsilanti, MichiganRecruiting
- Illinois CancerCare - WashingtonWashington, IllinoisRecruiting
- Illinois CancerCare-BloomingtonBloomington, IllinoisRecruiting
- Illinois CancerCare-CantonCanton, IllinoisRecruiting
- Illinois CancerCare-CarthageCarthage, IllinoisRecruiting
- Illinois CancerCare-DixonDixon, IllinoisRecruiting
- Illinois CancerCare-EurekaEureka, IllinoisRecruiting
- Illinois CancerCare-GalesburgGalesburg, IllinoisRecruiting
- Illinois CancerCare-Kewanee ClinicKewanee, IllinoisRecruiting
- Illinois CancerCare-MacombMacomb, IllinoisRecruiting
- Illinois CancerCare-Ottawa ClinicOttawa, IllinoisRecruiting
- Illinois CancerCare-PekinPekin, IllinoisRecruiting
- Illinois CancerCare-PeoriaPeoria, IllinoisRecruiting
- Illinois CancerCare-PeruPeru, IllinoisRecruiting
- Illinois CancerCare-PrincetonPrinceton, IllinoisRecruiting
- Iowa Methodist Medical CenterDes Moines, IowaRecruiting
- IRMC Cancer CenterIndiana, PennsylvaniaRecruiting
- Jefferson HospitalJefferson Hills, PennsylvaniaRecruiting
- Jersey City Medical CenterJersey City, New JerseyRecruiting
- Johns Hopkins University/Sidney Kimmel Cancer CenterBaltimore, MarylandRecruiting
- Kadlec Clinic Hematology and OncologyKennewick, WashingtonRecruiting
- Karmanos Cancer Institute at McLaren Greater LansingLansing, MichiganRecruiting
- Katmai Oncology GroupAnchorage, AlaskaRecruiting
- Kootenai Clinic Cancer Services - Post FallsPost Falls, IdahoRecruiting
- Kootenai Clinic Cancer Services - SandpointSandpoint, IdahoRecruiting
- Kootenai Health - Coeur d'AleneCoeur d'Alene, IdahoRecruiting
- Lahey ClinicBurlington, MassachusettsRecruiting
- Lahey Clinic PeabodyPeabody, MassachusettsRecruiting
- Lankenau Medical CenterWynnewood, PennsylvaniaRecruiting
- Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, New YorkRecruiting
- Lawrence Memorial HospitalLawrence, KansasRecruiting
- Legacy Cancer Institute Medical Oncology and Day TreatmentVancouver, WashingtonRecruiting
- Legacy Good Samaritan Hospital and Medical CenterPortland, OregonRecruiting
- Legacy Meridian Park HospitalTualatin, OregonRecruiting
- Legacy Mount Hood Medical CenterGresham, OregonRecruiting
- Legacy Salmon Creek HospitalVancouver, WashingtonRecruiting
- Lehigh Valley Hospital - MuhlenbergBethlehem, PennsylvaniaRecruiting
- Lehigh Valley Hospital-Cedar CrestAllentown, PennsylvaniaRecruiting
- Lehigh Valley Hospital-HazletonHazleton, PennsylvaniaRecruiting
- Lenox Hill HospitalNew York, New YorkRecruiting
- Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerSavannah, GeorgiaRecruiting
- Loma Linda University Medical CenterLoma Linda, CaliforniaRecruiting
- Loyola University Medical CenterMaywood, IllinoisRecruiting
- LSU Health Sciences Center at ShreveportShreveport, LouisianaRecruiting
- Manhattan Eye Ear and Throat HospitalNew York, New YorkRecruiting
- Marshfield Medical Center - MinocquaMinocqua, WisconsinRecruiting
- Marshfield Medical Center - WestonWeston, WisconsinRecruiting
- Marshfield Medical Center-EC Cancer CenterEau Claire, WisconsinRecruiting
- Marshfield Medical Center-MarshfieldMarshfield, WisconsinRecruiting
- Marshfield Medical Center-Rice LakeRice Lake, WisconsinRecruiting
- Marshfield Medical Center-River Region at Stevens PointStevens Point, WisconsinRecruiting
- Mease Countryside HospitalSafety Harbor, FloridaRecruiting
- Medical Center of the RockiesLoveland, ColoradoRecruiting
- Medical College of WisconsinMilwaukee, WisconsinRecruiting
- Medical Oncology Hematology Consultants PANewark, DelawareRecruiting
- Medical University of South CarolinaCharleston, South CarolinaRecruiting
- Memorial Health University Medical CenterSavannah, GeorgiaRecruiting
- Memorial Hospital EastShiloh, IllinoisRecruiting
- Memorial Hospital WestPembroke Pines, FloridaRecruiting
- Memorial Medical CenterModesto, CaliforniaRecruiting
- Memorial Regional Hospital/Joe DiMaggio Children's HospitalHollywood, FloridaRecruiting
- Mercy HospitalCedar Rapids, IowaRecruiting
- Mercy HospitalCoon Rapids, MinnesotaRecruiting
- Mercy Hospital Fort SmithFort Smith, ArkansasRecruiting
- Mercy Hospital Oklahoma CityOklahoma City, OklahomaRecruiting
- Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
- Mercy Hospital SouthSt Louis, MissouriRecruiting
- Mercy Medical CenterBaltimore, MarylandRecruiting
- Mercy Medical Center - Des MoinesDes Moines, IowaRecruiting
- Mercy Oncology and Hematology - Clayton-ClarksonBallwin, MissouriRecruiting
- Mercyhealth Hospital and Cancer Center - JanesvilleJanesville, WisconsinRecruiting
- MetroHealth Medical CenterCleveland, OhioRecruiting
- Miami Valley Cancer Care and InfusionGreenville, OhioRecruiting
- Miami Valley HospitalDayton, OhioRecruiting
- Miami Valley Hospital NorthDayton, OhioRecruiting
- Miami Valley Hospital SouthCenterville, OhioRecruiting
- Mills Health CenterSan Mateo, CaliforniaRecruiting
- Minnesota Oncology - BurnsvilleBurnsville, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-ChaskaChaska, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-WoodburyWoodbury, MinnesotaRecruiting
- Missouri Baptist Medical CenterSt Louis, MissouriRecruiting
- Missouri Baptist Sullivan HospitalSullivan, MissouriRecruiting
- Monmouth Medical CenterLong Branch, New JerseyRecruiting
- Monmouth Medical Center Southern CampusLakewood, New JerseyRecruiting
- Morristown Medical CenterMorristown, New JerseyRecruiting
- Morton Plant HospitalClearwater, FloridaRecruiting
- Mount Sinai ChelseaNew York, New YorkRecruiting
- Mount Sinai HospitalNew York, New YorkRecruiting
- Mount Sinai Medical CenterMiami Beach, FloridaRecruiting
- Mount Sinai WestNew York, New YorkRecruiting
- Munson Medical CenterTraverse City, MichiganRecruiting
- MyMichigan Medical Center SaginawSaginaw, MichiganRecruiting
- MyMichigan Medical Center TawasTawas City, MichiganRecruiting
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, ArkansasRecruiting
- Newark Beth Israel Medical CenterNewark, New JerseyRecruiting
- Newton Medical CenterNewton, New JerseyRecruiting
- North Memorial Medical Health CenterRobbinsdale, MinnesotaRecruiting
- Northern Westchester HospitalMount Kisco, New YorkRecruiting
- Northwest Cancer Center - Crown PointCrown Point, IndianaRecruiting
- Northwest Cancer Center - HobartHobart, IndianaRecruiting
- Northwest Cancer Center - ValparaisoValparaiso, IndianaRecruiting
- Northwest Medical Specialties PLLCTacoma, WashingtonRecruiting
- Northwest Oncology LLCDyer, IndianaRecruiting
- Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
- Northwestern Medicine Glenview Outpatient CenterGlenview, IllinoisRecruiting
- Northwestern Medicine Grayslake Outpatient CenterGrayslake, IllinoisRecruiting
- Northwestern Medicine Lake Forest HospitalLake Forest, IllinoisRecruiting
- Northwestern Medicine Oak BrookOak Brook, IllinoisRecruiting
- Northwestern Medicine Orland ParkOrland Park, IllinoisRecruiting
- Northwestern UniversityChicago, IllinoisRecruiting
- NYU Langone Hospital - BrooklynBrooklyn, New YorkRecruiting
- NYU Langone Hospital - Long IslandMineola, New YorkRecruiting
- Ochsner LSU Health Monroe Medical CenterMonroe, LouisianaRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- OhioHealth Mansfield HospitalMansfield, OhioRecruiting
- OhioHealth Marion General HospitalMarion, OhioRecruiting
- OhioHealth Pickerington Methodist HospitalPickerington, OhioRecruiting
- OhioHealth Westerville Medical Campus/Westerville Cancer CenterWesterville, OhioRecruiting
- Oncology Associates at Mercy Medical CenterCedar Rapids, IowaRecruiting
- OptumCare Cancer Care at CharlestonLas Vegas, NevadaRecruiting
- OptumCare Cancer Care at Fort ApacheLas Vegas, NevadaRecruiting
- OSF Saint Anthony Medical CenterRockford, IllinoisRecruiting
- OSF Saint Francis Hospital and Medical GroupEscanaba, MichiganRecruiting
- Overlook HospitalSummit, New JerseyRecruiting
- Palo Alto Medical Foundation Health CarePalo Alto, CaliforniaRecruiting
- Palo Alto Medical Foundation-FremontFremont, CaliforniaRecruiting
- Palo Alto Medical Foundation-Santa CruzSanta Cruz, CaliforniaRecruiting
- Palo Alto Medical Foundation-SunnyvaleSunnyvale, CaliforniaRecruiting
- Paoli Memorial HospitalPaoli, PennsylvaniaRecruiting
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, MinnesotaRecruiting
- Parkland Health Center - FarmingtonFarmington, MissouriRecruiting
- Phelps Memorial Hospital CenterSleepy Hollow, New YorkRecruiting
- Pocono Medical CenterEast Stroudsburg, PennsylvaniaRecruiting
- Poudre Valley HospitalFort Collins, ColoradoRecruiting
- Premier Blood and Cancer CenterDayton, OhioRecruiting
- Prisma Health Cancer Institute - ButternutGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - EasleyEasley, South CarolinaRecruiting
- Prisma Health Cancer Institute - EastsideGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - FarisGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - GreerGreer, South CarolinaRecruiting
- Prisma Health Cancer Institute - SenecaSeneca, South CarolinaRecruiting
- Prisma Health Cancer Institute - SpartanburgBoiling Springs, South CarolinaRecruiting
- Prisma Health Greenville Memorial HospitalGreenville, South CarolinaRecruiting
- ProMedica Flower HospitalSylvania, OhioRecruiting
- Providence Hood River Memorial HospitalHood River, OregonRecruiting
- Providence Medical Foundation - Santa RosaSanta Rosa, CaliforniaRecruiting
- Providence Newberg Medical CenterNewberg, OregonRecruiting
- Providence Portland Medical CenterPortland, OregonRecruiting
- Providence Regional Cancer System-LaceyLacey, WashingtonRecruiting
- Providence Saint Vincent Medical CenterPortland, OregonRecruiting
- Providence Santa Rosa Memorial HospitalSanta Rosa, CaliforniaRecruiting
- Providence Willamette Falls Medical CenterOregon City, OregonRecruiting
- Regional Cancer Center-Lee Memorial Health SystemFort Myers, FloridaRecruiting
- Regions HospitalSaint Paul, MinnesotaRecruiting
- Renown Regional Medical CenterReno, NevadaRecruiting
- Riddle Memorial HospitalMedia, PennsylvaniaRecruiting
- Ridgeview Medical CenterWaconia, MinnesotaRecruiting
- Riverside Methodist HospitalColumbus, OhioRecruiting
- Robert Wood Johnson University Hospital SomersetSomerville, New JerseyRecruiting
- Roper HospitalCharleston, South CarolinaRecruiting
- Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
- Rutgers New Jersey Medical SchoolNewark, New JerseyRecruiting
- Saint Alphonsus Cancer Care Center-BoiseBoise, IdahoRecruiting
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, IdahoRecruiting
- Saint Alphonsus Cancer Care Center-NampaNampa, IdahoRecruiting
- Saint Alphonsus Cancer Care Center-OntarioOntario, OregonRecruiting
- Saint Anthony Regional HospitalCarroll, IowaRecruiting
- Saint Catherine HospitalIndianapolis, IndianaRecruiting
- Saint Charles Health SystemBend, OregonRecruiting
- Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
- Saint Francis Regional Medical CenterShakopee, MinnesotaRecruiting
- Saint John's Hospital - HealtheastMaplewood, MinnesotaRecruiting
- Saint Joseph's Hospital/Children's Hospital-TampaTampa, FloridaRecruiting
- Saint Joseph's/Candler - Bluffton CampusBluffton, South CarolinaRecruiting
- Saint Luke's Cancer Center - AllentownAllentown, PennsylvaniaRecruiting
- Saint Luke's Cancer Institute - BoiseBoise, IdahoRecruiting
- Saint Luke's Cancer Institute - FruitlandFruitland, IdahoRecruiting
- Saint Luke's Cancer Institute - MeridianMeridian, IdahoRecruiting
- Saint Luke's Cancer Institute - NampaNampa, IdahoRecruiting
- Saint Luke's Hospital - Monroe CampusStroudsburg, PennsylvaniaRecruiting
- Saint Luke's Hospital - Upper Bucks CampusQuakertown, PennsylvaniaRecruiting
- Saint Luke's Hospital of DuluthDuluth, MinnesotaRecruiting
- Saint Luke's Hospital-Anderson CampusEaston, PennsylvaniaRecruiting
- Saint Luke's University Hospital-Bethlehem CampusBethlehem, PennsylvaniaRecruiting
- Saint Mary Medical CenterHobart, IndianaRecruiting
- Saint Vincent HospitalErie, PennsylvaniaRecruiting
- Saint Vincent Hospital Cancer Center at Oconto FallsOconto Falls, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at SheboyganSheboygan, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center Green BayGreen Bay, WisconsinRecruiting
- Sainte Genevieve County Memorial HospitalSainte Genevieve, MissouriRecruiting
- Salina Regional Health CenterSalina, KansasRecruiting
- Schulze Family Foundation Cancer Clinic - Bonita Health CenterBonita Springs, FloridaRecruiting
- Shaw Cancer CenterEdwards, ColoradoRecruiting
- Sibley Memorial HospitalWashington D.C., District of ColumbiaRecruiting
- SIH Cancer InstituteCarterville, IllinoisRecruiting
- Sinai Hospital of BaltimoreBaltimore, MarylandRecruiting
- Siteman Cancer Center at Christian HospitalSt Louis, MissouriRecruiting
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, MissouriRecruiting
- Siteman Cancer Center at West County HospitalCreve Coeur, MissouriRecruiting
- Siteman Cancer Center-South CountySt Louis, MissouriRecruiting
- Smilow Cancer Hospital Care Center - GuilfordGuilford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center - WaterfordWaterford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center - WesterlyWesterly, Rhode IslandRecruiting
- Smilow Cancer Hospital Care Center at GlastonburyGlastonbury, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center at GreenwichGreenwich, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center at Long RidgeStamford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center at Saint FrancisHartford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center-FairfieldFairfield, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center-TrumbullTrumbull, ConnecticutRecruiting
- Smilow Cancer Hospital-Derby Care CenterDerby, ConnecticutRecruiting
- Smilow Cancer Hospital-Torrington Care CenterTorrington, ConnecticutRecruiting
- Smilow Cancer Hospital-Waterbury Care CenterWaterbury, ConnecticutRecruiting
- South Carolina Cancer Specialists PCHilton Head Island, South CarolinaRecruiting
- Southeastern Medical Oncology Center-ClintonClinton, North CarolinaRecruiting
- Southeastern Medical Oncology Center-GoldsboroGoldsboro, North CarolinaRecruiting
- Southeastern Medical Oncology Center-JacksonvilleJacksonville, North CarolinaRecruiting
- Southern Illinois University School of MedicineSpringfield, IllinoisRecruiting
- Springfield ClinicSpringfield, IllinoisRecruiting
- Springfield Memorial HospitalSpringfield, IllinoisRecruiting
- State University of New York Upstate Medical UniversitySyracuse, New YorkRecruiting
- Staten Island University HospitalStaten Island, New YorkRecruiting
- Stony Brook University Medical CenterStony Brook, New YorkRecruiting
- SUNY Upstate Medical Center-Community CampusSyracuse, New YorkRecruiting
- Sutter Auburn Faith HospitalAuburn, CaliforniaRecruiting
- Sutter Medical Center SacramentoSacramento, CaliforniaRecruiting
- Sutter Pacific Medical FoundationSanta Rosa, CaliforniaRecruiting
- Sutter Roseville Medical CenterRoseville, CaliforniaRecruiting
- Sutter Solano Medical Center/Cancer CenterVallejo, CaliforniaRecruiting
- Swedish Cancer Institute-EdmondsEdmonds, WashingtonRecruiting
- Swedish Cancer Institute-IssaquahIssaquah, WashingtonRecruiting
- Swedish Medical Center-First HillSeattle, WashingtonRecruiting
- SWOGSacramento, CaliforniaRecruiting
- The Angeles Clinic and Research Institute - West Los Angeles OfficeLos Angeles, CaliforniaRecruiting
- The Cancer Institute at Saint Francis HospitalEast Hills, New YorkRecruiting
- The Cancer Institute of New Jersey HamiltonHamilton, New JerseyRecruiting
- The Community HospitalMunster, IndianaRecruiting
- The Philips Family Cancer CenterSouthampton, New YorkRecruiting
- The University of Kansas Cancer Center - OlatheOlathe, KansasRecruiting
- ThedaCare Regional Cancer CenterAppleton, WisconsinRecruiting
- ThedaCare Regional Medical Center - NeenahNeenah, WisconsinRecruiting
- Tidelands Georgetown Memorial HospitalGeorgetown, South CarolinaRecruiting
- Torrance Memorial Physician Network - Cancer CareTorrance, CaliforniaRecruiting
- Touro InfirmaryNew Orleans, LouisianaRecruiting
- Tower Cancer Research FoundationBeverly Hills, CaliforniaRecruiting
- Trinitas Hospital and Comprehensive Cancer Center - Williamson Street CampusElizabeth, New JerseyRecruiting
- Trinity Health Grand Rapids HospitalGrand Rapids, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, MichiganRecruiting
- Trinity Health Medical Center - BrightonBrighton, MichiganRecruiting
- Trinity Health Medical Center - CantonCanton, MichiganRecruiting
- Trinity Health Muskegon HospitalMuskegon, MichiganRecruiting
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, MichiganRecruiting
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, MichiganRecruiting
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, MichiganRecruiting
- Trinity Medical CenterMoline, IllinoisRecruiting
- Tufts Medical CenterBoston, MassachusettsRecruiting
- UCHealth - Cherry CreekDenver, ColoradoRecruiting
- UCHealth Greeley HospitalGreeley, ColoradoRecruiting
- UCHealth Highlands Ranch HospitalHighlands Ranch, ColoradoRecruiting
- UCHealth Lone Tree Health CenterLone Tree, ColoradoRecruiting
- UCHealth University of Colorado HospitalAurora, ColoradoRecruiting
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, CaliforniaRecruiting
- UCI Health - Yorba LindaYorba Linda, CaliforniaRecruiting
- UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, IowaRecruiting
- UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, IowaRecruiting
- UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, IowaRecruiting
- UI Healthcare Mission Cancer and Blood - Fort DodgeFort Dodge, IowaRecruiting
- UM Baltimore Washington Medical Center/Tate Cancer CenterGlen Burnie, MarylandRecruiting
- UM Upper Chesapeake Hematology and Oncology - AberdeenAberdeen, MarylandRecruiting
- UM Upper Chesapeake Medical CenterBel Air, MarylandRecruiting
- UNC Health Cancer Care CaryCary, North CarolinaRecruiting
- UNC Health Cancer Care GarnerGarner, North CarolinaRecruiting
- UNC Health Cancer Care RaleighRaleigh, North CarolinaRecruiting
- UNC Health Cancer Care WakefieldRaleigh, North CarolinaRecruiting
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, North CarolinaRecruiting
- United HospitalSaint Paul, MinnesotaRecruiting
- University Health Truman Medical CenterKansas City, MissouriRecruiting
- University Medical Center New OrleansNew Orleans, LouisianaRecruiting
- University of Alabama at Birmingham Cancer CenterBirmingham, AlabamaRecruiting
- University of Arizona Cancer Center-North CampusTucson, ArizonaRecruiting
- University of Arizona Cancer Center-Orange Grove CampusTucson, ArizonaRecruiting
- University of Arkansas for Medical SciencesLittle Rock, ArkansasRecruiting
- University of IllinoisChicago, IllinoisRecruiting
- University of Kansas Cancer CenterKansas City, KansasRecruiting
- University of Kansas Cancer Center - BriarcliffKansas City, MissouriRecruiting
- University of Kansas Cancer Center - Lee's SummitLee's Summit, MissouriRecruiting
- University of Kansas Cancer Center - NorthKansas City, MissouriRecruiting
- University of Kansas Cancer Center-Overland ParkOverland Park, KansasRecruiting
- University of Kansas Health System Saint Francis CampusTopeka, KansasRecruiting
- University of Kansas Hospital-Indian Creek CampusOverland Park, KansasRecruiting
- University of Kansas Hospital-Westwood Cancer CenterWestwood, KansasRecruiting
- University of Kentucky/Markey Cancer CenterLexington, KentuckyRecruiting
- University of Maryland/Greenebaum Cancer CenterBaltimore, MarylandRecruiting
- University of Michigan - Brighton Center for Specialty CareBrighton, MichiganRecruiting
- University of Michigan Health - Sparrow LansingLansing, MichiganRecruiting
- University of Michigan Health - WestWyoming, MichiganRecruiting
- University of Michigan Rogel Cancer CenterAnn Arbor, MichiganRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Pittsburgh, PennsylvaniaRecruiting
- University of Texas Health Science Center at San AntonioSan Antonio, TexasRecruiting
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
- UPMC Cancer Center at UPMC NorthwestSeneca, PennsylvaniaRecruiting
- UPMC Cancer Center-Natrona HeightsNatrona Heights, PennsylvaniaRecruiting
- UPMC Cancer Center-WashingtonWashington, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - Passavant - CranberryCranberry Township, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Butler Health SystemButler, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center in CoraopolisMoon Township, PennsylvaniaRecruiting
- UPMC MemorialYork, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC West Mifflin-Cancer Center JeffersonWest Mifflin, PennsylvaniaRecruiting
- UPMC Western MarylandCumberland, MarylandRecruiting
- UPMC-Heritage Valley Health System BeaverBeaver, PennsylvaniaRecruiting
- UPMC-Johnstown/John P. Murtha Regional Cancer CenterJohnstown, PennsylvaniaRecruiting
- UPMC-Magee Womens HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint MargaretPittsburgh, PennsylvaniaRecruiting
- Upper Valley Medical CenterTroy, OhioRecruiting
- Upstate Cancer Center at OswegoOswego, New YorkRecruiting
- Upstate Cancer Center at VeronaVerona, New YorkRecruiting
- UT MD Anderson - League CityLeague City, TexasRecruiting
- UT MD Anderson - Sugar LandSugar Land, TexasRecruiting
- UT MD Anderson - The WoodlandsConroe, TexasRecruiting
- UT MD Anderson - West HoustonHouston, TexasRecruiting
- UT MD Anderson Cancer CenterHouston, TexasRecruiting
- UW Health Carbone Cancer Center RockfordRockford, IllinoisRecruiting
- VCU Community Memorial Health CenterSouth Hill, VirginiaRecruiting
- VCU Massey Cancer Center at Stony PointRichmond, VirginiaRecruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
- Vince Lombardi Cancer Clinic - OshkoshOshkosh, WisconsinRecruiting
- Vince Lombardi Cancer Clinic-SheboyganSheboygan, WisconsinRecruiting
- Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, WisconsinRecruiting
- Virginia Cancer InstituteRichmond, VirginiaRecruiting
- Washington University School of MedicineSt Louis, MissouriRecruiting
- Wayne State University/Karmanos Cancer InstituteDetroit, MichiganRecruiting
- Weisberg Cancer Treatment CenterFarmington Hills, MichiganRecruiting
- West Michigan Cancer CenterKalamazoo, MichiganRecruiting
- West Virginia University Charleston DivisionCharleston, West VirginiaRecruiting
- West Virginia University HealthcareMorgantown, West VirginiaRecruiting
- Wexford Health and Wellness PavilionWexford, PennsylvaniaRecruiting
- William E Kahlert Regional Cancer Center/Sinai HospitalWestminster, MarylandRecruiting
- Winter Haven HospitalWinter Haven, FloridaRecruiting
- Women and Infants HospitalProvidence, Rhode IslandRecruiting
- Women's Diagnostic Center - MunsterMunster, IndianaRecruiting
- Yale UniversityNew Haven, ConnecticutRecruiting
- Yale-New Haven Hospital North Haven Medical CenterNorth Haven, ConnecticutRecruiting
- Yolanda G Barco Oncology InstituteMeadville, PennsylvaniaRecruiting
- Caro Cancer CenterCaro, MichiganSuspended
- Genesee Hematology Oncology PCFlint, MichiganSuspended
- Glens Falls HospitalGlens Falls, New YorkSuspended
- Jupiter Medical CenterJupiter, FloridaActive Not Recruiting
- MU Health - University Hospital/Ellis Fischel Cancer CenterColumbia, MissouriSuspended
- MU Health Care Goldschmidt Cancer CenterJefferson City, MissouriActive Not Recruiting
- Ochsner LSU Health - Cancer Treatment CenterShreveport, LouisianaSuspended
- Oklahoma Cancer Specialists and Research Institute-TulsaTulsa, OklahomaSuspended
- Oncology Hematology Associates of Saginaw Valley PCSaginaw, MichiganSuspended
- Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, MichiganSuspended
- SSM Health Good SamaritanMount Vernon, IllinoisSuspended
- UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, CaliforniaSuspended
- University of Kansas Cancer Center at North Kansas City HospitalNorth Kansas City, MissouriSuspended
- Zuckerberg San Francisco General HospitalSan Francisco, CaliforniaActive Not Recruiting
Puerto Rico2 locations · 2 recruiting
- Centro Comprensivo de Cancer de UPRSan JuanRecruiting
- PROncologySan JuanRecruiting
Who to ask about joining
Site Public Contactgingerreeves@uabmc.edu
Site Public Contact907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Site Public Contact520-694-8900
Who can join
This study is open to adults aged 18 and older, including men and women. Participants must have hormone receptor positive and HER2 negative breast cancer that is either stage II or III. Those with previous treatments or metastatic disease cannot join. The trial team will check to confirm eligibility.
What happens during the trial
Participants will first undergo testing to determine their MammaPrint score. Based on the results, they will be placed into one of two treatment groups: one group will receive standard chemotherapy, while the other group will receive chemotherapy along with durvalumab. Everyone will receive either chemotherapy or chemotherapy plus the immunotherapy. Participants will also have regular testing and may need to provide blood or tissue samples.
The trial team
The National Cancer Institute (NCI) is sponsoring this trial. Erin F. Cobain from the SWOG Cancer Research Network is the principal investigator leading the study.
Important dates
The trial started on November 27, 2023, and is expected to finish by May 31, 2032. It is currently recruiting new participants.
Additional information
This trial is in Phase 3, which means it is looking at how well the treatment works and how safe it is. The trial is FDA-regulated and aims to include about 3,680 participants.
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