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Surgical Oncologist, specializing in Dermatologic Cancers, Breast Cancer, Hematologic Cancers, Medical Oncologist, Surgical Oncologist, specializing in Dermatologic Cancers, Breast Cancer, Hematologic Cancers
Dr. Steven A. Rosenberg, MD, PhD, is an internationally recognized surgical oncologist and immunotherapy pioneer, best known for his groundbreaking work in cancer immunology and the development of adoptive cell transfer therapies. He serves as Chief of the Surgery Branch at the National Cancer Institute, where he has led transformative research in cellular and gene-based cancer treatments. Dr. Rosenberg earned his medical degree and PhD in biophysics from the University of Chicago and completed his surgical residency at Peter Bent Brigham Hospital in Boston. He is board-certified in Surgery and has dedicated his career to advancing novel immunotherapeutic strategies for patients with advanced malignancies.
A trailblazer in the field of tumor immunology, Dr. Rosenberg was the first to demonstrate the effective use of interleukin-2 (IL-2) in treating metastatic melanoma and renal cell carcinoma. He pioneered adoptive cell transfer, including tumor-infiltrating lymphocyte (TIL) therapy and genetically engineered T-cell approaches, laying the foundation for modern CAR T-cell therapies. His research has directly shaped the field of immuno-oncology, leading to treatments that have extended survival for patients with otherwise refractory cancers. He has authored more than 1,100 peer-reviewed publications and his work has fundamentally influenced cancer biology, translational science, and clinical oncology worldwide.
In addition to his scientific achievements, Dr. Rosenberg is a respected educator and mentor, having trained generations of physician-scientists who now lead major immunotherapy programs globally. He has received numerous prestigious awards, including the Lasker~DeBakey Clinical Medical Research Award, the Keio Medical Science Prize, and election to the National Academy of Sciences and the National Academy of Medicine. Through his lifelong commitment to research, clinical innovation, and mentorship, Dr. Steven A. Rosenberg has defined the field of cancer immunotherapy and continues to transform the landscape of cancer treatment.
