Dr. Matthias A.Karajannis

Dr. Matthias A. Karajannis, MD, MS, is a pediatric neuro-oncologist and Chief of the Pediatric Neuro-Oncology Service at Memorial Sloan Kettering Cancer Center, where he has cared for children with brain tumors, spinal cord tumors, and neurofibromatosis for more than two decades. He completed medical school during a period of rapid advances in pediatric oncology, a time that shaped his understanding of how collaboration between laboratory and clinical research can transform once-deadly cancers into curable diseases. After completing his pediatric residency and a fellowship in pediatric hematology/oncology, he pursued additional specialized training in pediatric neuro-oncology, driven by the recognition that many children with brain tumors were not achieving good outcomes and that new, more effective therapies with fewer side effects were urgently needed. At MSK, he works within a multidisciplinary team of medical and surgical experts who combine clinical skill with advances in molecular diagnostics to practice precision medicine, identifying the unique biological characteristics and vulnerabilities of each tumor to guide personalized treatment plans.