Surgeon, specializing in Dermatologic Cancers
Dr. Charlotte E. Ariyan, MD, PhD, is a highly accomplished surgical oncologist at Memorial Sloan Kettering Cancer Center (MSKCC), where she specializes in the treatment of melanoma and other skin cancers. She earned her medical degree and PhD in immunology from Yale University, followed by a residency in general surgery at NewYork-Presbyterian/Columbia and a fellowship in surgical oncology at MSKCC. Board-certified in General Surgery, she currently practices at MSK’s Manhattan and regional outpatient locations, offering advanced surgical care for patients with complex cutaneous malignancies. Her approach incorporates both traditional and minimally invasive techniques, with a focus on personalized, multidisciplinary cancer treatment.
Dr. Ariyan is widely recognized for her research in tumor immunology and her pioneering role in integrating surgery with immune checkpoint inhibitor therapy for melanoma. She has contributed to pivotal studies exploring how immunotherapy can be safely and effectively combined with surgery to improve outcomes in advanced melanoma. Her investigations have also examined predictors of response to immunotherapy and the role of neoadjuvant approaches in high-risk skin cancer. In addition to her clinical trials work, she has published extensively in top-tier journals on topics related to tumor-infiltrating lymphocytes, immunotherapy timing, and durable outcomes in melanoma patients.
Beyond her surgical and research expertise, Dr. Ariyan is a dedicated educator and leader at MSKCC. She is actively involved in training surgical residents and oncology fellows and contributes to clinical guideline development in melanoma care. Her work has earned recognition within national surgical and oncology societies, and she frequently presents at international meetings on advances in melanoma treatment. Through her clinical innovation, research leadership, and commitment to education, Dr. Ariyan stands out as a leading expert in the surgical management of melanoma and immunotherapy-integrated cancer care.
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