Dr. Randall F. Holcombe

Dr. Randall F. Holcombe, MD, MBA, is a nationally recognized medical oncologist and health services leader specializing in gastrointestinal cancers. He serves as Director of the University of Vermont Cancer Center and has held prior leadership positions at the Icahn School of Medicine at Mount Sinai and the University of Hawai‘i Cancer Center. Dr. Holcombe earned his medical degree from Cornell University Medical College, completed his residency training in internal medicine at Brigham and Women’s Hospital, and pursued fellowship training in medical oncology at the Dana-Farber Cancer Institute. He is board-certified in Internal Medicine and Medical Oncology and is respected for his leadership in academic oncology.

Dr. Holcombe’s research focuses on colorectal and gastrointestinal cancers, with contributions to translational research, clinical trials, and health services delivery. He has been a principal investigator on studies evaluating novel systemic therapies and has published extensively in peer-reviewed journals. He is also noted for his work in cancer care disparities, community engagement, and developing cancer center programs that expand access to high-quality care.

Beyond his research and clinical expertise, Dr. Holcombe is a committed educator and mentor. He has trained oncology fellows and junior faculty while leading institutional initiatives to improve multidisciplinary care. He has served in leadership roles within ASCO and other national organizations, helping to shape policies that advance oncology practice. Through his dedication to patient care, research, and health services leadership, Dr. Randall Holcombe continues to influence cancer care delivery at both regional and national levels.